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Proteomics Ezine


Journal Highlight: Proteomics: present and future in fish, shellfish and seafood Journal Highlight: Proteomics: present and future in fish, shellfish and seafood  [registered users only]
A brief overview of current classical proteomics methodology (electrophoresis and mass spectrometry) is presented and focused in the context of applications beneficial to the field of fish, shellfish and seafood/seafood products. [April 23, 2012]


Seafood spoilers: Streptococcal bacteria in vacuum-packed seafood product isolated and characterised Seafood spoilers: Streptococcal bacteria in vacuum-packed seafood product isolated and characterised 
A pathogen that causes streptococcosis in fish has been isolated from a spoiled sample of refrigerated, vacuum-packed seafood and characterised by genotyping and proteomic analysis. The mass spectrum of its soluble proteins displays several peaks that are unique to this species and will allow its rapid identification in food products. [April 15, 2012]


Cancer classification: MALDI imaging distinguishes different types of cancer Cancer classification: MALDI imaging distinguishes different types of cancer 
Six common types of tumour have been differentiated by mass spectrometry in a proof-of-principle proteomics study by European scientists, which could lead to a personalised treatment regime for cancer sufferers. [April 1, 2012]


Monthly Highlight

<font size=3>FREE Webinar from Thermo Scientific</font><br />Capturing States of Pluripotency: How Cell Surface Chemoproteomics Facilitates Rapid Immunophenotyping and Sorting of Pluripotent Stem Cells FREE Webinar from Thermo Scientific
Capturing States of Pluripotency: How Cell Surface Chemoproteomics Facilitates Rapid Immunophenotyping and Sorting of Pluripotent Stem Cells
 

Induction of a pluripotent state in somatic cells through nuclear reprogramming has ushered in a new era of regenerative medicine. However, heterogeneity and varied differentiation potentials among induced pluripotent stem cell (iPSC) lines challenge our ability to identify and isolate functionally defined cell populations for disease modeling, drug discovery, and patient therapies. Thus, there is an urgent need to develop non-genetic methods for isolating more homogeneous, functionally defined iPSCs.

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Mass Spectrometry Blog

60th ASMS on Twitter 
[May 17, 2012]

Dynamic Periodic Table 
[May 12, 2012]

Cyclotrons 
[May 3, 2012]

Calutrons 
[April 15, 2012]

The Physical Chemistry of Polymers 
[January 27, 2012]

Monthly Highlight

<font size=3>FREE Webinar from Thermo Scientific</font><br />Peptide Targeted Quantification by High Resolution Mass Spectrometry: A Paradigm Shift? FREE Webinar from Thermo Scientific
Peptide Targeted Quantification by High Resolution Mass Spectrometry: A Paradigm Shift?
 

Traditionally, targeted peptide quantification studies have used a triple quadrupole (QQQ) mass spectrometer because of their high throughput capabilities and high sensitivity, allowing for large numbers of proteins to be quantified in a single LC/MS experiment. However, the transition from discovery to targeted verification and quantification can still be slow and cumbersome due to the transition between different mass spectrometer platforms.

In this webinar, new approaches to peptide-targeted quantification using high-resolution and accurate mass (HR/AM) mass spectrometry are introduced, together with the new Q Exactive high-performance benchtop quadrupole-Orbitrap LC-MS/MS.

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and is now available on-demand.

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