Copper, on the beat with NMR
The first NMR spectroscopy study of the copper site in an important blue metalloprotein, azurin, has been undertaken. Copper mediates many biochemical redox reactions and azurin plays an important role in catalysing electron transfer in cellular reactions.
[March 1, 2010]
Pinpointing prostate problems without surgery
Magnetic resonance spectroscopy, the molecular cousin of MRI could be used to pinpoint the exact location of prostate cancers and to determine the aggressiveness of a tumour, according to research published in the Science Translational Medicine. The approach could help guide treatment.
[February 15, 2010]
Two-dimensional J-resolved NMR spectroscopy: review of a key methodology in the metabolomics toolbox
[registered users only]
Two-dimensional
1H
J-resolved (JRES) NMR spectroscopy is widely used in metabolomics studies of plants and animals. This review provides a basic introduction to the technique and then discusses and recommends key strategies for both spectral acquisition and processing. Strategies for implementing JRES spectroscopy into the metabolomics toolbox are then considered, including for metabolic fingerprinting, metabolite identification and metabolite quantification.
[February 3, 2010]