.... http://www.spectroscopyNOW.com/coi/cda/landing.cda?type=Feature&chId=10 http://www.spectroscopyNOW.com/coi/cma/download.cma?imageType=RssLogo&contentType=Feature&siteId=1&chId=10 http://www.spectroscopynow.com/ http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26743&type=Feature&page=1 A comparative study of the protein contents in male and female human plasma has revealed some important differences which could be exploited to prevent the occurrence of transfusion-related acute lung injury which can occur following blood transfusion. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26677&type=Feature&page=1 This review gives an overview of the directions in which exercise-proteome research is moving and examines the main tools that can be used as a novel strategy in exercise physiology investigation. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26654&type=Feature&page=1 Proteins adsorbed onto the surfaces of titanium-based biomaterials that are used as implants and artificial joints have been identified by a proteomics technique which could lead to the development of novel materials with improved bioreactivity. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26608&type=Feature&page=1 A record number of ancient proteins have been isolated and identified from the femur of a 43,000 year-old woolly mammoth that had been preserved in permafrost, using specially developed techniques to minimise contamination along with high-resolution mass spectrometry. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26477&type=Feature&page=1 New mass spectrometry-based approaches that are being applied to lens research were highlighted and the future direction of proteomics cataract research was outlined. Mass spectrometry hold great promise to determine which crystallin post-translational modifications lead to a cataract. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26504&type=Feature&page=1 The unacceptably low survival rate of cloned animals might be related to the aberrant expression of proteins associated with oxidative damage, apoptosis and senescence, say Korean scientists. The restoration of normal placental protein levels could increase the efficiency and help to save endangered species. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26447&type=Feature&page=1 An unknown black market product seized by German customs agents was found to contain fibroblast growth factor, say European scientists. The protein, which has not been given full clinical approval, was probably intended for illegal sports doping. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26411&type=Feature&page=1 The current status of the Human Protein Atlas project, which provides an important source of information for numerous biomedical research projects, including biomarker discovery efforts, is reviewed. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26401&type=Feature&page=1 Several innate immunity proteins have been identified in the nasal lavage fluid of small children suffering from a respiratory virus infection, including full-length and truncated versions of an antibacterial protein which were implicated in higher risk factors for infant boys. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26332&type=Feature&page=1 The protein changes occurring in the part of the brain that deals with new memories have been charted during a spatial learning activity by rats in an international study which revealed two discrete change phases within 12 hours of training. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26302&type=Feature&page=1 A two-dimensional gel-based approach was used in this study to investigate time-dependent changes in the bovine whey proteome during the early lactation period. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26268&type=Feature&page=1 A proteomics study following proteins through the brewing process has suggested that the haze found in beers originates predominantly from barley proteins, rather than the hordein proteins in malt that had previously been implicated. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26218&type=Feature&page=1 Diagnosis of obstructive sleep apnoea based on serum protein levels took a step closer following a preliminary proteomic study on affected men in which the expression of some proteins was related to the severity of the condition. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26180&type=Feature&page=1 The development of the stone and formation of peach fruit were explored using a proteomic approach, revealing 68 proteins with different expression patterns in both the endocarp and mesocarp during early fruit development, the majority being involved in primary or secondary metabolism. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26161&type=Feature&page=1 The phosphoprotein signatures of archived prostate cancer tissues have been successfully characterised by a gel-free proteomics approach in a pilot study that can form the basis of a biomarker discovery campaign. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26074&type=Feature&page=1 Universal screening of newborn children for sickle cell disease is possible due to the development of a rapid mass spectrometric method designed to detect all types of haemoglobin variant and which can process up to 1000 samples a day. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26039&type=Feature&page=1 This review recapitulates how antibiotic proteomic signatures are established and highlights areas of antibiotic research benefiting most from proteomic signatures. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=26025&type=Feature&page=1 One of the risk factors associated with toxic oil syndrome has been identified in proteomics studies as a phenotype of haptoglobin, with a different phenotype affording protection, according to researchers in Spain where the disease struck. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=25966&type=Feature&page=1 Ocean acidification alters the proteome of the larvae of an ecologically important barnacle species, to a small but significant extent. Molecular chaperones and proteins related to energy metabolism and respiration had altered expression levels, hinting at the adopted mechanism for coping with acidification stress. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=10&id=25931&type=Feature&page=1 A roadmap for improving the success rate of clinical proteomics includes steps for improvements that need to be made in analytical tools, discovery, validation, clinical application, and post-clinical application appraisal.