.... http://www.spectroscopyNOW.com/coi/cda/landing.cda?type=Feature&chId=5 http://www.spectroscopyNOW.com/coi/cma/download.cma?imageType=RssLogo&contentType=Feature&siteId=1&chId=5 http://www.spectroscopynow.com/ http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26702&type=Feature&page=1 NMR spectroscopy has the potential to predict the prognosis and response to treatment of patients with low-grade infiltrating brain cancer, gliomas, that have mutations in the isocitrate dehydrogenase 1 gene, according to new imaging studies based on the technique. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26628&type=Feature&page=1 Dried liquorice root contains substances that apparently stop tooth decay. Research published in the Journal of the American Chemical Society describes the isolation and NMR spectroscopic analysis of key components. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26593&type=Feature&page=1 The sigma electrons in polycyclic oligosilanes are delocalised across the Si-Si bonds of a three-dimensional silicon framework. Such frameworks are often present in crystalline and amorphous silicon and related silicon clusters, such as the persilastaffanes now investigated using NMR spectroscopy. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26508&type=Feature&page=1 Chemists in Europe have used dynamic combinatorial libraries (DCLs) to fish out macrocycles that are selective for different heavy metal ions. This classic supramolecular work extends an approach used widely in pharmaceutical drug discovery to good effect in an unrelated field. The team used NMR spectroscopy, X-ray diffraction and other techniques to study the optimal four macrocycles. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26487&type=Feature&page=1 A shaped pulse sequence is applied to suppress the eight 1H NMR frequencies of water and ethanol for measurement of a wide range of products from beer, over wine to high strength spirits up to 80% vol. The increase in signal-to-noise ratio is so significant that the quantitative control of legal limits of minor constituents such as methanol or acetaldehyde is now possible. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26431&type=Feature&page=1 NMR spectroscopy has been used to determine lipid levels in patients with the skin disorder psoriasis. The results point to a possible explanation for a link with cardiovascular disease. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26386&type=Feature&page=1 Researchers at the Institut Rayonnement Matière de Saclay in Gif-sur-Yvette, France, have developed a novel method for converting the greenhouse gas, carbon dioxide, into either useable building blocks for chemical syntheses or new fuels. The team used nuclear magnetic resonance spectroscopy to track progress of their reactions. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26321&type=Feature&page=1 Pulsed-field gradient nuclear magnetic resonance (PFG-NMR) spectroscopy and single molecule fluorescent spectroscopy have been used to probe a fundamental physical phenomenon - an ergodic experiment that reveals how a dynamic system gives the same mean result as would a single particle in repeated experiments. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26262&type=Feature&page=1 Researchers in the UK and Portugal, have used NMR spectroscopy to reveal a new way in which nature makes heme - the component that gives blood its colour and allows red blood cells to carry oxygen around the body. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26202&type=Feature&page=1 Membrane proteins mediate so much of the information flow between cells and their surroundings. Understanding their molecular structure will inevitably give scientists insights into function and form as well as providing targets for novel pharmaceuticals when these proteins go awry. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26147&type=Feature&page=1 A new NMR screening technique for testing samples of unlisted but illicit street drugs, often sold as "bath salts", can reveal components not normally detected by standard chromatographic methods, according to researchers speaking at the meeting of the American Chemical Society at the end of August. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26054&type=Feature&page=1 A new generation of power supply materials with a high energy density is being keenly sought by the manufacturers of electric vehicles, notebook computers and other portable devices. A novel supercapacitor material studied with NMR and IR spectroscopy and other techniques could be suitable for replacing current rechargeable battery materials. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=26009&type=Feature&page=1 NMR spectroscopy has provided researchers with insights into how parasitic organisms exploit nutrients provided by the host organism. The work could open up a new approach to finding unique drug targets and in the present study, specifically against the tropical parasite Leishmania. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=25954&type=Feature&page=1 Biomolecular NMR experts in Germany have discovered how the U2AF protein facilitates the process of splicing used by cells to make the correct template for RNA transcription and the subsequent expression of proteins. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=25872&type=Feature&page=1 A US team has paired the remote-detection version of NMR spectroscopy with a chromatography technique used in microfluidic devices. The work opens the way to portable and highly sensitive multi-dimensional chemical analysis. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=25782&type=Feature&page=1 Many observers suggest that hydrogen produced from sustainable sources could lead us into a low-carbon economy that derives its energy from renewable sources rather than fossil fuels. NMR spectroscopy has played a part in experiments that demonstrate how so-called "baking soda" might help researchers cook up a safe way to store this hazardous gas. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=25690&type=Feature&page=1 The molecular equivalent of M.C. Escher's optical illusion of the perpetually climbing stair has been constructed by Japanese chemists and tracked with NMR spectroscopy. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=25668&type=Feature&page=1 Noroviruses attach to their host cells through histo blood group antigens (HBGAs), and compounds that interfere with this interaction are likely to be of therapeutic or diagnostic interest. It is shown that NMR binding studies can simultaneously identify and differentiate the site for binding HBGA ligands and complementary ligands from a large compound library, thereby facilitating the design of potent heterobifunctional ligands. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=25581&type=Feature&page=1 US researchers have demonstrated magnet-free nuclear magnetic resonance, opening up the possibility of low-cost, portable chemical analysis. Writing in the journal Nature Physics, the team says that it is just the beginning for the development of zero-field NMR although the team has already demonstrated that it is possible to get, clear, highly specific spectra. http://www.spectroscopyNOW.com/coi/cda/detail.cda?chId=5&id=25470&type=Feature&page=1 Cassis base 345B, undecavertol, 1,3-oxathiane oxane, isospirene... Perfume can be so romantic! But the chemical components underpinning the often-enticing and seductive smells of fragrances are, one might say equal parts art and science. One of the most intriguing elements of several fragrances, including popular perfumes like Le monde est beau by Daniela Andrier and DKNY Be Delicious by Maurice Roucel is the fruity top note - blackcurrant.