SERS , Raman , and DFT analyses of fentanyl and carfentanil: Toward detection of trace samples

Skip to Navigation

EarlyView Article

  • Published: Aug 24, 2017
  • Author: Jennifer Leonard, Abed Haddad, Omar Green, Ronald L. Birke, Thomas Kubic, Ali Kocak, John R. Lombardi
  • Journal: Journal of Raman Spectroscopy

Abstract

We examine the normal Raman and the surface‐enhanced Raman spectra of fentanyl and carfentanil. As an aid in the assignment of the spectral lines, we present a density functional theory calculation. Although Raman spectroscopy is a valuable analytic tool for the detection and identification of molecular species, it is a weak effect and requires specialized equipment for detection of trace samples. We therefore turn to surface‐enhanced Raman spectroscopy, which utilizes the large enhancement of the Raman signal endowed by proximity to silver or gold nanoparticles. The enhancement factor (EF) obtained in this experiment is ≥1.6 × 105. This points the way towards future development of a simple and sensitive technique for the detection of analytes in trace quantities, particularly for wider application in forensic science.

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in separation science? Visit our sister site separationsNOW.com

Copyright © 2017 John Wiley & Sons, Inc. All Rights Reserved