Journal Highlight: Nanoscale chemical imaging using tip-enhanced Raman spectroscopy: A critical review

Skip to Navigation

Ezine

  • Published: Jul 2, 2013
  • Author: spectroscopyNOW
  • Channels: Raman
thumbnail image: Journal Highlight: Nanoscale chemical imaging using tip-enhanced Raman spectroscopy: A critical review
This review focuses on the prerequisites for the efficient coupling of light to the tip as well as the shortcomings and pitfalls that have to be considered for tip-enhanced Raman spectroscopy imaging, for its application to nanoscale analysis.

Nanoscale chemical imaging using tip-enhanced Raman spectroscopy: A critical review

Angewandte Chemie International Edition, 2013, 52, 5940-5954
Thomas Schmid, Lothar Opilik, Carolin Blum, Renato Zenobi

Abstract: Methods for chemical analysis at the nanometer scale are crucial for understanding and characterizing nanostructures of modern materials and biological systems. Tip-enhanced Raman spectroscopy (TERS) combines the chemical information provided by Raman spectroscopy with the signal enhancement known from surface-enhanced Raman scattering (SERS) and the high spatial resolution of atomic force microscopy (AFM) or scanning tunneling microscopy (STM). A metallic or metallized tip is illuminated by a focused laser beam and the resulting strongly enhanced electromagnetic field at the tip apex acts as a highly confined light source for Raman spectroscopic measurements. This review focuses on the prerequisites for the efficient coupling of light to the tip as well as the shortcomings and pitfalls that have to be considered for TERS imaging, a fascinating but still challenging way to look at the nanoworld. Finally, examples from recent publications have been selected to demonstrate the potential of this technique for chemical imaging with a spatial resolution of approximately 10 nm and sensitivity down to the single-molecule level for applications ranging from materials sciences to life sciences.

  • This paper is free to view for all users registered on spectroscopyNOW.com until the end of August 2013.
    After this time, you can purchase it using Pay-Per-View on Wiley Online Library.

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Most Viewed

Copyright Information

Interested in separation science? Visit our sister site separationsNOW.com

Copyright © 2017 John Wiley & Sons, Inc. All Rights Reserved