Journal Highlight: Value of MRI of the hand and the wrist in evaluation of bone age: Preliminary results

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  • Published: May 26, 2014
  • Author: spectroscopyNOW
  • Channels: MRI Spectroscopy
thumbnail image: Journal Highlight: Value of MRI of the hand and the wrist in evaluation of bone age: Preliminary results
Bone age was determined using MRI of the hand and wrist and the data could be useful for developing an atlas of skeletal development and bone age.


Value of MRI of the hand and the wrist in evaluation of bone age: Preliminary results

Journal of Magnetic Resonance Imaging, 2014, 39, 1198-1205
Ernesto Tomei, Alessandro Sartori, Daniel Nissman, Najwa Al Ansari, Sofia Battisti, Antonello Rubini, Andrea Stagnitti, Milvia Martino, Mario Marini, Ersilia Barbato and Richard C. Semelka

Abstract: Bone age was determined using MRI of the hand and wrist. A total of 179 (78 female and 101 males, 11 to 16 years old) subjects of 252 normal volunteers met entrance criteria. A low field open magnet (0.2 Tesla) was used for this study; coronal T1-weighted images with a slice thickness of 1.3 mm were acquired. Two blinded radiologists evaluated the studies and the following elements were considered: the appearance of cartilage, vacuolization of cartilage, provisional calcification, progression of ossification, and complete ossification. Correlation between chronologic age and MR bone age was determined by means of simple linear regression analysis. Strong correlation between MR skeletal age and chronological age was observed for both investigators, with a Pearson correlation R2 = 0.9 for each. Determination of bone age with MRI is feasible and shows good interobserver reproducibility. Data from this study may be useful to develop an atlas of skeletal development and bone age.

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