Journal Highlight: Plasma-based ambient mass spectrometry techniques: The current status and future prospective

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  • Published: Jul 6, 2015
  • Author: spectroscopyNOW
  • Channels: Base Peak
thumbnail image: Journal Highlight: Plasma-based ambient mass spectrometry techniques: The current status and future prospective
An overview is presented of the key concepts, mechanisms and applications of plasma-based ambient mass spectrometry techniques, and the challenges and outlook are discussed.

Plasma-based ambient mass spectrometry techniques: The current status and future prospective

Mass Spectrometry Reviews, 2015, 34, 449-473
Xuelu Ding and Yixiang Duan

Abstract: Plasma-based ambient mass spectrometry is emerging as a frontier technology for direct analysis of sample that employs low-energy plasma as the ionization reagent. The versatile sources of ambient mass spectrometry (MS) can be classified according to the plasma formation approaches; namely, corona discharge, glow discharge, dielectric barrier discharge, and microwave-induced discharge. These techniques allow pretreatment-free detection of samples, ranging from biological materials (e.g., flies, bacteria, plants, tissues, peptides, metabolites, and lipids) to pharmaceuticals, food-stuffs, polymers, chemical warfare reagents, and daily-use chemicals. In most cases, plasma-based ambient MS performs well as a qualitative tool and as an analyzer for semi-quantitation. Herein, we provide an overview of the key concepts, mechanisms, and applications of plasma-based ambient MS techniques, and discuss the challenges and outlook.

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