Journal Highlight: Real-time in vivo cancer diagnosis using Raman spectroscopy

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  • Published: Aug 3, 2015
  • Author: spectroscopyNOW
  • Channels: Raman
thumbnail image: Journal Highlight: Real-time in vivo cancer diagnosis using Raman spectroscopy
An overview is presented on the latest development of real-time in vivo Raman systems for cancer detection, covering instrumentation, data handling, oncology applications and the diagnosis of different kinds of cancer.

Real-time in vivo cancer diagnosis using Raman spectroscopy

Journal of Biophotonics, 2015, 8, 527-545
Wenbo Wang, Jianhua Zhao, Michael Short and Haishan Zeng

Abstract: Raman spectroscopy has becoming a practical tool for rapid in vivo tissue diagnosis. This paper provides an overview on the latest development of real-time in vivo Raman systems for cancer detection. Instrumentation, data handling, as well as oncology applications of Raman techniques were covered. Optic fiber probes designs for Raman spectroscopy were discussed. Spectral data pre-processing, feature extraction, and classification between normal/benign and malignant tissues were surveyed. Applications of Raman techniques for clinical diagnosis for different types of cancers, including skin cancer, lung cancer, stomach cancer, oesophageal cancer, colorectal cancer, cervical cancer, and breast cancer, were summarized.

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