New Application Note: Determination of Tartrate in Drug Products in Just 10 Minutes

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  • Published: May 24, 2012
  • Source: Thermo Fisher Scientific
  • Suppliers: Thermo Fisher Scientific
  • Channels: Ion Chromatography

May 24, 2012.

Thermo Fisher Scientific is pleased to announce two new ion chromatography (IC) methods designed to reduce time and labor and increase accuracy when determining tartrate in drug products containing tolterodine tartrate. Application Note 1002: Determination of Tartaric Acid in Tolterodine Tartrate Drug Products by IC with Suppressed Conductivity Detection demonstrates that these methods are accurate and reproducible, with analysis times as low as 10 minutes. Both approaches use an electrolytic suppressor, which eliminates the time and effort to prepare dilute sulfuric acid regenerant.

The first method uses a Reagent-Free™ IC (RFIC™) system and therefore requires only the addition of deionized water for eluent and suppressor regenerant production. This 10-minute method demonstrates improved accuracy and productivity because both eluent and regenerant are prepared automatically, eliminating the time and effort required to manually prepare these reagents while also reducing the possibility of errors and contamination. The second method uses a carbonate/bicarbonate eluent and has an analysis time of 12 minutes.

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About Thermo Fisher Scientific

Thermo Fisher Scientific Inc. is the world leader in serving science. Our mission is to enable our customers to make the world healthier, cleaner and safer. With revenues of $12 billion, we have approximately 39,000 employees and serve customers within pharmaceutical and biotech companies, hospitals and clinical diagnostic labs, universities, research institutions and government agencies, as well as in environmental and process control industries. We create value for our key stakeholders through three premier brands, Thermo Scientific, Fisher Scientific and Unity™ Lab Services, which offer a unique combination of innovative technologies, convenient purchasing options and a single solution for laboratory operations management. Our products and services help our customers solve complex analytical challenges, improve patient diagnostics and increase laboratory productivity. Visit

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