Bruker launches new range of analytical technologies

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impact II

Bruker has launched a suite of analytical products based around their new impact II ultra-high resolution Qq-time-of-flight mass spectrometer. All these products, together with the impact II, were launched at the recent American Society for Mass Spectrometry (ASMS) Conference on Mass Spectrometry and Allied Topics in Baltimore, US.

Impact II is designed for use with ultra high performance liquid chromatography (UHPLC) for applications requiring trace analysis of complex matrices, including proteomics, biomarker research and residue screening. In particular, Bruker claims that systems comprising UHPLC and impact II can conduct: quantitative analysis of proteomics samples, including bottom-up proteomics, glycomics and identifying post-translational modifications; high-throughput proteoform screening of intact proteins, allowing over 1000 proteofoms to be screened in less than 30 minutes; and fast analysis of sub-units of monoclonal antibodies.

The products that Bruker has launched in support of impact II include two new software platforms, MaxQuant and Compass PathwayScreener, and a new forensic toxicology platform called ToxScreener. MaxQuant is designed for analyzing large collections of high resolution mass spectrometry data, while PathwayScreener works with Bruker’s existing ProfileAnalysis software to perform pathway-driven, targeted analysis of metabolomics data for non-targeted data mining and biomarker discovery. ToxScreener comprises an accurate mass database covering drugs of forensic relevance and allows forensic scientists to screen for thousands of known or unknown forensic compounds, including both conventional illegal drugs and new designer drugs.

‘The new products deliver outstanding and robust performance in a very accessible and cost-effective platform,’ says Ole Vorm, vice president of Bruker’s Life-Science Research & Proteomics business unit. ‘We are conscious of enhancing the reach and capabilities of UHF-QTOF and nano-electrospray ionization such that we make this innovative technology readily available and accessible − also for biologists who may not be mass-spec experts.’

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