Radio ion chromatography

Positron emission tomography (PET) is one of the most powerful noninvasive diagnostic tools for tracing organ functioning. Quality control of the short-lived PET-radiopharmaceuticals is challenging, not least because of the tough time limits, the radiation issue and the near nanomole radiotracer quantities produced.

Metrohm`s highly customizable chromatography system copes with the tough requirements of the radiopharmaceutical industry and pharmacopoeial regulations. One single multi-channel radio IC meets the quality control requirements of various production lines. Besides the high quality, the Metrohm IC presented ensures user`s safety, low maintenance costs, and outstanding ruggedness.

This poster presents a versatile multi-channel radio IC system that controls the production of the radionuclide [18F]fluoride (precursor) and the two radiotracers synthesized from it, [18F]fluorodeoxyglucose and [18F]fluorocholine, in accordance to pharmacopoeial regulations.

Read the full Application Note (IC AN-8.000.6090EN, PDF: 554KB)