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Introduction to Pharmaceutical Chemical Analysis

Date: Dec 16, 2011

Author: Steen Hansen, Stig Pedersen-Bjergaard, Knut Rasmussen

This textbook is the first to present a systematic introduction to chemical analysis of pharmaceutical raw materials, finished pharmaceutical products, and of drugs in biological fluids, which are carried out in pharmaceutical laboratories worldwide. In addition, this textbook teaches the fundamentals of all the major analytical techniques used in the pharmaceutical laboratory, and teaches the international pharmacopoeias and guidelines of importance for the field. It is primarily intended for the...

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Mathematical Methods for Physical and Analytical Chemistry

Date: Nov 15, 2011

Author: David Z. Goodson

Mathematical Methods for Physical and Analytical Chemistry presents mathematical and statistical methods to students of chemistry at the intermediate, post-calculus level. The content includes a review of general calculus; a review of numerical techniques often omitted from calculus courses, such as cubic splines and Newton’s method; a detailed treatment of statistical methods for experimental data analysis; complex numbers; extrapolation; linear algebra; and differential equations. With...

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Organic Spectroscopy Workbook

Date: Sep 2, 2011

Author: Tom Forrest, Jean-Pierre Rabine, Michel Rouillard

Spectroscopy is used in physical and analytical chemistry for the identification of substances through the spectrum emitted from or absorbed by them. The derivation of structural information from spectroscopic data is now an integral part of many courses in chemistry and related subjects at most universities. This workbook: Features exercises to help develop the student's understanding of how structures are determined from spectra and to promote the student's own interpretation of different spectra....

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Comprehensive Chromatography in Combination with Mass Spectrometry

Date: Aug 26, 2011

Author: Luigi Mondello

This book provides a detailed description of various multidimensional chromatographic separation techniques. The editor first provides an introduction to the area and then dives right into the various complex separation techniques. While still not used routinely comprehensive chromatography techniques will help acquaint the readers with the fundamentals and possible benefits of multi-dimensional separations coupled with mass spectrometry. The topics include a wide range of material that will appease all...

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Handbook of High-resolution Spectroscopy

Date: Aug 19, 2011

Author: Martin Quack, Frederic Merkt

The field of High-Resolution Spectroscopy has been considerably extended and even redefined in some areas. Combining the knowledge of spectroscopy, laser technology, chemical computation, and experiments, Handbook of High-Resolution Spectroscopy provides a comprehensive survey of the whole field as it presents itself today, with emphasis on the recent developments. This essential handbook for advanced research students, graduate students, and researchers takes a systematic approach through the range of...

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Vibrational Optical Activity: Principles and Applications

Date: Aug 12, 2011

Author: Laurence A. Nafie

This unique book stands as the only comprehensive introduction to vibrational optical activity (VOA) and is the first single book that serves as a complete reference for this relatively new, but increasingly important area of molecular spectroscopy. Key features: A single-source reference on this topic that introduces, describes the background and foundation of this area of spectroscopy. Serves as a guide on how to use it to carry out applications with relevant problem solving. Depth and breadth of...

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Pharmaceutical Anti-Counterfeiting: Combating the Real Danger from Fake Drugs

Date: Aug 12, 2011

Author: Mark Davison

This book overviews and integrates the business and technical issues that pharmaceutical companies need to know in order to combat the major global problem of counterfeit medicines. In addition to discussion of the problems, the author Davison addresses analytical techniques scientists use to detect counterfeits and presents some possible solutions to the threat of counterfeit medical products. Coverage moves from basic overview of the problem, costs / risks to consumers (toxic products, mistrust of drug...

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Illicit Drugs in the Environment: Occurrence, Analysis, and Fate using Mass Spectrometry

Date: May 13, 2011

Author: Sara Castiglioni, Ettore Zuccato, Roberto Fanelli

Illicit drugs are an emerging class of environmental contaminants and mass spectrometry is the technique of choice for their analysis. This landmark reference discusses the analytical techniques used to detect illicit drugs in wastewater and surface water, details how to estimate the levels of contaminants in the environment, and explores the behavior, fate, and toxic effects of this new class of contaminants, now a ubiquitous presence in wastewater and surface water. The book details how an estimate of...

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Platelet Proteomics: Principles, Analysis, and Applications

Date: May 10, 2011

Author: Ángel García-Alonso, Yotis Senis

The purpose of the book is to introduce platelets, and their functional role in thrombotic and cardiovascular disease, justifying the relevance of platelet proteomics research. Focus then shifts to the recent developments on mass spectrometry (MS)-based proteomics.  This chapter shows potential applications for platelet proteomics not yet carried out.  It includes examples of post-translational modifications (PTMs) analysis in platelets. The second part of the book focuses on the main research...

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Mass Spectrometry in Drug Metabolism and Disposition: Basic Principles and Applications

Date: Apr 26, 2011

Author: Mike S. Lee, Mingshe Zhu

This book examines the background, industrial context, process, analytical methodology, and technology of metabolite identification. It emphasizes the applications of metabolite identification in drug research. While primarily a textbook, the book also functions as a comprehensive reference to those in the industry. The authors have worked closely together and combine complementary backgrounds to bring technical and cultural awareness to this very important endeavor while serving to address needs within...

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