Real-time MRI at a resolution of 20 ms

Skip to Navigation


  • Published: Sep 28, 2010
  • Channels: MRI Spectroscopy
thumbnail image: Real-time MRI at a resolution of 20 ms
Real-time MRI at a resolution of 20 ms
Martin Uecker, Shuo Zhang, Dirk Voit, Alexander Karaus, Klaus-Dietmar Merboldt and Jens Frahm
NMR in Biomedicine 2010, 23, 986-994

Real-time MRI reconstructions as a function of acquisition time or degree of undersampling. Nonlinear inverse reconstructions with temporal and spatial filtering of diastolic (top) and systolic (bottom) frames from real-time MRI movies of the human heart (in-plane resolution, 2.0 mm; section thickness, 8 mm; TR = 2.0 ms) acquired from only 9 spokes (imaging time, 18 ms).

Abstract: The desire to visualize noninvasively physiological processes at high temporal resolution has been a driving force for the development of MRI since its inception in 1973. In this article, we describe a unique method for real-time MRI that reduces image acquisition times to only 20 ms. Although approaching the ultimate limit of MRI technology, the method yields high image quality in terms of spatial resolution, signal-to-noise ratio and the absence of artifacts. As proposed previously, a fast low-angle shot (FLASH) gradient-echo MRI technique (which allows for rapid and continuous image acquisitions) is combined with a radial encoding scheme (which offers motion robustness and moderate tolerance to data undersampling) and, most importantly, an iterative image reconstruction by regularized nonlinear inversion (which exploits the advantages of parallel imaging with multiple receiver coils). In this article, the extension of regularization and filtering to the temporal domain exploits consistencies in successive data acquisitions and thereby enhances the degree of radial undersampling in a hitherto unexpected manner by one order of magnitude. The results obtained for turbulent flow, human speech production and human heart function demonstrate considerable potential for real-time MRI studies of dynamic processes in a wide range of scientific and clinical settings.

  • This paper is free to view to spectroscopyNOW registered users until November 20, 2010. After this time it will be available via Wiley's Pay-Per-View service for US$29.95.
  • Click here to access the abstract of this paper. From here you can progress to read the full paper.
  • Click here for more details about NMR in Biomedicine


Social Links

Share This Links

Bookmark and Share


Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Copyright Information

Interested in separation science? Visit our sister site

Copyright © 2018 John Wiley & Sons, Inc. All Rights Reserved