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It is brain surgery

Date: Jul 1, 2010

Author: David Bradley

MRI allows surgeons to safely and effectively operate inside the human brain through small incisions in the natural creases of the eyelid rather than drilling through skull to get to the grey matter at the front of the brain.

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NMR metabolic profile of human follicular fluid

Date: Jun 28, 2010

Author:

The metabolic profiles of human follicular fluid samples that were obtained using NMR spectroscopy are analysed in this work. High correlations were found between important intermediaries of the energetic metabolic pathways of the follicle which can indicate the importance of these pathways in oocyte development. Some of these identified metabolites might be useful as biomarkers of the follicle maturation state, allowing the selection of oocytes in order to increase the pregnancy rates in women after in...

Read More thumbnail image: NMR metabolic profile of human follicular fluid

Thinking about a good night's sleep

Date: Jun 1, 2010

Author: David Bradley

Even a single night where a person suffers partial sleep deprivation (PSD) is enough to have a negative impact on thinking. A functional magnetic resonance imaging (fMRI) study suggests that as cognition and affective processing are disrupted, sleep pressure must represent a basic physiological constraint of brain function.

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Magnetic resonance histology of the adult zebrafish brain: optimization of fixation and gadolinium contrast enhancement

Date: May 24, 2010

Author:

In this study, the authors created the first protocol for optimal imaging of the adult zebrafish brain. This protocol has enabled the team to achieve the highest isotropic resolution for any vertebrate brain and is similar in thickness to traditional histological slices.

Read More thumbnail image: Magnetic resonance histology of the adult zebrafish brain optimization of fixation and gadolinium contrast enhancement

Reporting on contrasting MRI enzyme

Date: May 1, 2010

Author: David Bradley

Researchers have developed an extracellular enzymatic gene-reporter system for magnetic resonance imaging (MRI). The system yields strong, reversible contrast changes in response to the expression of secreted alkaline phosphatise. The products of SEAP activity can then be detected using an iron oxide based sensor.

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Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3.0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimer's disease

Date: Apr 27, 2010

Author:

Pseudo-continuous ASL provides a reliable whole brain CBF measurement in young and elderly adults whose results converge with those obtained with the traditional 15O-water PET perfusion imaging method. It is an alternative method for non-invasive in vivo examination of early pathophysiological changes in AD.

Read More thumbnail image: Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3_0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimers disease

A sound approach to fibroids

Date: Apr 1, 2010

Author: David Bradley

A new interventional radiology tool based on using MRI to guide focused high-energy ultrasound could be used to thermally ablate uterine fibroid tissue and relieve symptoms of this condition without major invasive surgery.

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Fat and water magnetic resonance imaging

Date: Mar 23, 2010

Author:

A wide variety of fat suppression and water-fat separation methods are used to suppress fat signal and improve visualization of abnormalities. This article reviews the most commonly used techniques for fat suppression and fat-water imaging.

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MRI on the ball

Date: Mar 1, 2010

Author: David Bradley

MRI proves to be a good diagnostic tool for testicular cancer and could spare some men unnecessary surgery.

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Pinpointing prostate problems without surgery

Date: Feb 15, 2010

Author: David Bradley

Magnetic resonance spectroscopy, the molecular cousin of MRI could be used to pinpoint the exact location of prostate cancers and to determine the aggressiveness of a tumour, according to research published in the Science Translational Medicine. The approach could help guide treatment.

Read More thumbnail image: Pinpointing prostate problems without surgery
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