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Dollar signs switch on brain

Date: Sep 1, 2010

Author: David Bradley

Functional magnetic resonance imaging has revealed a region of the brain about two inches above the left eyebrow that lights up whenever a person anticipating a reward for a task performed successfully is shown a dollar sign. The response is linked to dopamine release in response to pre-determined cues of which a symbol for money is one.

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Quantification of human body fat tissue percentage by MRI

Date: Aug 18, 2010

Author:

In this paper, a novel comprehensive and automatic analysis method for the determination and quantification of subcutaneous fat tissue and visceral fat tissue volumes either in the whole human body or in selected slices or regions of interest is shown.

Read More thumbnail image: Quantification of human body fat tissue percentage by MRI

MRI monitors anticancer nanotubes

Date: Aug 1, 2010

Author: David Bradley

Magnetic resonance imaging can now be used to monitor carbon nanotubes aimed at destroying tumour cells by laser induced heating, according to US researchers.

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Age- and sex-related differences in muscle phosphocreatine and oxygenation kinetics during high-intensity exercise in adolescents and adults

Date: Jul 26, 2010

Author:

The aim of this investigation was to examine the adaptation of the muscle phosphates implicated in regulating oxidative phosphorylation, and oxygenation at the onset of high intensity exercise in children and adults.

Read More thumbnail image: Age- and sex-related differences in muscle phosphocreatine and oxygenation kinetics during high-intensity exercise in adolescents and adults

It is brain surgery

Date: Jul 1, 2010

Author: David Bradley

MRI allows surgeons to safely and effectively operate inside the human brain through small incisions in the natural creases of the eyelid rather than drilling through skull to get to the grey matter at the front of the brain.

Read More thumbnail image: It is brain surgery

NMR metabolic profile of human follicular fluid

Date: Jun 28, 2010

Author:

The metabolic profiles of human follicular fluid samples that were obtained using NMR spectroscopy are analysed in this work. High correlations were found between important intermediaries of the energetic metabolic pathways of the follicle which can indicate the importance of these pathways in oocyte development. Some of these identified metabolites might be useful as biomarkers of the follicle maturation state, allowing the selection of oocytes in order to increase the pregnancy rates in women after in...

Read More thumbnail image: NMR metabolic profile of human follicular fluid

Thinking about a good night's sleep

Date: Jun 1, 2010

Author: David Bradley

Even a single night where a person suffers partial sleep deprivation (PSD) is enough to have a negative impact on thinking. A functional magnetic resonance imaging (fMRI) study suggests that as cognition and affective processing are disrupted, sleep pressure must represent a basic physiological constraint of brain function.

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Magnetic resonance histology of the adult zebrafish brain: optimization of fixation and gadolinium contrast enhancement

Date: May 24, 2010

Author:

In this study, the authors created the first protocol for optimal imaging of the adult zebrafish brain. This protocol has enabled the team to achieve the highest isotropic resolution for any vertebrate brain and is similar in thickness to traditional histological slices.

Read More thumbnail image: Magnetic resonance histology of the adult zebrafish brain optimization of fixation and gadolinium contrast enhancement

Reporting on contrasting MRI enzyme

Date: May 1, 2010

Author: David Bradley

Researchers have developed an extracellular enzymatic gene-reporter system for magnetic resonance imaging (MRI). The system yields strong, reversible contrast changes in response to the expression of secreted alkaline phosphatise. The products of SEAP activity can then be detected using an iron oxide based sensor.

Read More thumbnail image: Reporting on contrasting MRI enzyme

Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3.0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimer's disease

Date: Apr 27, 2010

Author:

Pseudo-continuous ASL provides a reliable whole brain CBF measurement in young and elderly adults whose results converge with those obtained with the traditional 15O-water PET perfusion imaging method. It is an alternative method for non-invasive in vivo examination of early pathophysiological changes in AD.

Read More thumbnail image: Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3_0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimers disease
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