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MRI nanoparticles seek and destroy cancer cells

Date: Jan 1, 2010

Author: David Bradley

A single nanoparticle can be tracked using real-time MRI as it homes in on cancer cells. A fluorescent dye used to tag the nanoparticle couples with heat therapy to kill the targeted cells.

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Diffusion tensor imaging of the human calf muscle

Date: Dec 22, 2009

Author:

Diffusion tensor imaging can display diffusional anisotropy of tissue. Possibly, proton diffusivity within the highly ordered musculature will change with muscle length since the cross sectional area of the muscle increases with shortening. Results show that the fractional anisotropy significantly decreases and the mean diffusion increases with muscle shortening.

Read More thumbnail image: Diffusion tensor imaging of the human calf muscle

MRI reveals BMI as bogus heart health indicator

Date: Dec 1, 2009

Author: David Bradley

Body mass index, BMI, is not a reliable indicator of overall fitness for obese individuals as assessed by internal, or visceral, fat. An MRI and NMR study reveals that fat accumulation in different parts of the body, such as around the heart and the aorta and within the liver, is associated with decreased heart function, but BMI offers no correlation for this problem.

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The development of the birdcage resonator: a historical perspective

Date: Nov 24, 2009

Author:

This personal account, taken from the current special 'coils' issue of NMR in Biomedicine, charts the development of the birdcage resonator, covering the historic context of early MRI development.

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Juggling matters on the brain

Date: Nov 1, 2009

Author: David Bradley

UK scientists have used magnetic resonance imaging to reveal that learning a complex task like juggling can causes changes in the white matter in the brain. The findings could have implications for developing new approaches to neurodegenerative diseases, such as multiple sclerosis.

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Morphology, binding behavior and MR-properties of paramagnetic collagen-binding liposomes

Date: Oct 22, 2009

Author:

Collagen is the major constituent of the extracellular matrix and responsible for maintaining the structural integrity of organs and tissues, and in pathological processes such as atherosclerosis and myocardial infarction. The diagnostics of the latter diseases using MRI could strongly benefit from the use of collagen-specific contrast agents. Read this outstanding paper selected by the Editor-in-Chief of the journal, Contrast Media & Molecular Imaging.

Read More thumbnail image: Morphology binding behavior and MR-properties of paramagnetic collagen-binding liposomes

Eye test betters MRI in stroke

Date: Oct 1, 2009

Author: David Bradley

US researchers have demonstrated proof of principle that a short and simple assessment of eye movements in suspected stroke patients can distinguish new strokes from other less serious disorders better than magnetic resonance imaging. The technique demonstrated only in a small-scale study could help screen patients complaining of dizziness, nausea, and spinning sensations.

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1H NMR metabolomics study of age profiling in children

Date: Sep 28, 2009

Author:

Metabolic profiling of urine provides a fingerprint of personalized endogenous metabolite markers that correlate to a number of factors such as gender, disease, diet, toxicity, medication, and age. In this study, age-related metabolic changes in children of age 12 years and below were analyzed by 1H NMR spectroscopy of urine. These results may be potentially useful in assessing the biological age (as opposed to chronological) of young humans as well as in providing a deeper understanding of the confounding...

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Tears and smiles bond secure mothers to baby

Date: Sep 1, 2009

Author: David Bradley

The sight of her baby's smile or even its tears cause the reward centres in a mother's brain to light up, according to an international functional magnetic resonance imaging (fMRI) study, but only if the mother herself had a secure attachment to her own parent.

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In ovo non-invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging

Date: Aug 14, 2009

Author:

Though, the chick embryo has long been used as a model for cardiovascular research, MRI has not yet been used for in vivo cardiac studies. This study used retrospectively gated Cine MRI to image the cardiac function of chick embryos in ovo, thus eliminating the need for ECG and respiratory gating The images were then analysed to quantify left ventricular functional parameters and mass.

Read More thumbnail image: In ovo non-invasive quantification of the myocardial function and mass of chick embryos using magnetic resonance imaging
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