MRI Spectroscopy / Ezine
Thinking about a good night's sleep
Date: Jun 1, 2010
Author: David Bradley
Even a single night where a person suffers partial sleep deprivation (PSD) is enough to have a negative impact on thinking. A functional magnetic resonance imaging (fMRI) study suggests that as cognition and affective processing are disrupted, sleep pressure must represent a basic physiological constraint of brain function.
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Magnetic resonance histology of the adult zebrafish brain: optimization of fixation and gadolinium contrast enhancement
Date: May 24, 2010
Author:
In this study, the authors created the first protocol for optimal imaging of the adult zebrafish brain. This protocol has enabled the team to achieve the highest isotropic resolution for any vertebrate brain and is similar in thickness to traditional histological slices.
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Reporting on contrasting MRI enzyme
Date: May 1, 2010
Author: David Bradley
Researchers have developed an extracellular enzymatic gene-reporter system for magnetic resonance imaging (MRI). The system yields strong, reversible contrast changes in response to the expression of secreted alkaline phosphatise. The products of SEAP activity can then be detected using an iron oxide based sensor.
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Reliability and precision of pseudo-continuous arterial spin labeling perfusion MRI on 3.0 T and comparison with 15O-water PET in elderly subjects at risk for Alzheimer's disease
Date: Apr 27, 2010
Author:
Pseudo-continuous ASL provides a reliable whole brain CBF measurement in young and elderly adults whose results converge with those obtained with the traditional 15O-water PET perfusion imaging method. It is an alternative method for non-invasive in vivo examination of early pathophysiological changes in AD.
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A sound approach to fibroids
Date: Apr 1, 2010
Author: David Bradley
A new interventional radiology tool based on using MRI to guide focused high-energy ultrasound could be used to thermally ablate uterine fibroid tissue and relieve symptoms of this condition without major invasive surgery.
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Fat and water magnetic resonance imaging
Date: Mar 23, 2010
Author:
A wide variety of fat suppression and water-fat separation methods are used to suppress fat signal and improve visualization of abnormalities. This article reviews the most commonly used techniques for fat suppression and fat-water imaging.
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MRI on the ball
Date: Mar 1, 2010
Author: David Bradley
MRI proves to be a good diagnostic tool for testicular cancer and could spare some men unnecessary surgery.
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Pinpointing prostate problems without surgery
Date: Feb 15, 2010
Author: David Bradley
Magnetic resonance spectroscopy, the molecular cousin of MRI could be used to pinpoint the exact location of prostate cancers and to determine the aggressiveness of a tumour, according to research published in the Science Translational Medicine. The approach could help guide treatment.
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Red lenses
Date: Feb 1, 2010
Author: David Bradley
US scientists have used MRI to show that apparently the less you use your brain's frontal lobes, the more you perceive your behaviour through rose-tinted spectacles. They publish details in the February issue of the journal NeuroImage.
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MRS of the occipital cortex and the cerebellar vermis distinguishes individual cats affected with alpha-mannosidosis from normal cats
Date: Jan 25, 2010
Author:
In vivo MRS from the cerebellar vermis and occipital cortex of cats with alpha mannosidosis (AMD) demonstrated a broad signal between 3.4 - 4.3 ppm (arrowed) from undigested oligosaccharides, which was not observed in normal cats. High-resolution NMR spectra of perchloric acid extracts confirmed the presence of accumulated oligosaccharides along with increased resonances from Glc-NAc and anomeric sugar protons in tissues from AMD cats. This characteristic MRS pattern may be used for diagnosis and treatment...
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