Base Peak

Now in its 15th year, Base Peak is the world's leading mass spectrometry resource and is dedicated to all aspects of MS including hyphenated techniques such as LC-MS and GC-MS, and related applications such as proteomics, pharmaceutical analysis, food quality analysis, environmental analysis, drug targeting and discovery as well as forensics and drug testing. 

Monthly Highlight

Last Month's Most Accessed Feature: Palaeolithic glues: High-resolution mass spectrometry classification

The secrets of Palaeolithic glues will be unearthed more readily using a new method that combines 2D GC with high-resolution time-of-flight mass spectrometry and allows lower headspace SPME temperatures to be used, preserving artefact integrity.

Read More thumbnail image: Last Month's Most Accessed Feature: Palaeolithic glues: High-resolution mass spectrometry classification

2018 Free Sample Issues of Key Analytical Science Journals

The 2018 free sample issues of all our Analytical Chemistry journals are now available!

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Advertorial Feature

Shimadzu Europa
High-Throughput Multicomponent Profiling of Cell Culture Medium by LC/MS/MS for Advance Process Monitoring of Biopharmaceutical Products

thumbnail image: <font size=3>Shimadzu Europa</font><br />High-Throughput Multicomponent Profiling of Cell Culture Medium by LC/MS/MS for Advance Process Monitoring of Biopharmaceutical Products

“Method Package for Cell Culture Profiling” enables users to analyze simultaneously multicomponents of cell culture medium using UHPLC coupled with triple quadrupole mass spectrometry. This package covers analysis method not only for basal medium of cell culture but also metabolites secreted by cells.

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Ezines

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A novel system for assessing drug-protein binding that combines nanopore optical interferometry with mass spectrometry has been developed to accelerate the drug discovery process.

Intact, highly‐charged protein ions have been formed on high vacuum TOF mass spectrometers in linear and reflectron modes by effective matrix removal from sample surfaces and charged clusters, suggesting mechanistic links to traditional ionization methods of electrospray ionization and matrix‐assisted laser desorption/ionization.

The classical forensic fingerprint technique of cyanoacrylate fuming is compatible with mass spectrometry imaging, say US researchers, who used an orbitrap system rather than time-of-flight techniques to improve performance and detect endogenous and exogenous substances.

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Education

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For over 20 years, each issue of the Journal of Mass Spectrometry has contained a Special Feature article. These are highly regarded in the mass spectrometry community and extremely popular with researchers around the globe. These features are freely available to the entire mass spec community.

Selected key technologies of the analytical science industry are discussed by Steve Down with reference to burgeoning application areas and the scope for future improvements.

Ion source pressure plays a significant role in the process of ionization and the subsequent ion transmission inside a mass spectrometer. Pressurizing the ion source to a gas pressure greater than atmospheric pressure is a relatively new approach that aims to further improve the performance of atmospheric pressure ionization sources. A brief review on the development of super-atmospheric pressure ion sources, including high-pressure electrospray, field desorption and superheated ESI, and the strategies to...

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Journals

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The Journal of Mass Spectrometry (JMS) publishes papers on a broad range of topics of interest to scientists working in both fundamental and applied areas involving the study of gaseous ions.

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