Journal Highlight: In pursuit of resolution in time-of-flight mass spectrometry: A historical perspective

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  • Published: Nov 7, 2016
  • Author: spectroscopyNOW
  • Channels: Base Peak
thumbnail image: Journal Highlight: In pursuit of resolution in time-of-flight mass spectrometry: A historical perspective
Time-of-flight mass spectrometry is reviewed from its inception in the 1940s to the present day. The review is concerned with fundamentals of time-of-flight analyzers and of ion sources to the extent that sources influence analyzers.

In pursuit of resolution in time-of-flight mass spectrometry: A historical perspective

Mass Spectrometry Reviews, 2016, 35, 738-757
Anna Radionova, Igor Filippov and Peter J Derrick

Abstract: Time-of-flight mass spectrometry is reviewed from its inception in the 1940s to the present day. The review is concerned with fundamentals of time-of-flight analyzers and of ion sources to the extent that sources influence analyzers. The patent literature has been covered, and efforts made to bring to light less well-known papers and studies. Linear TOF, the use of single and multiple mirrors, tandem TOF and the use of electrostatic analysers are covered. The provocative proposition remains that "time-of-flight will within the space of a few years be the method-of-choice for mass spectrometry, in the way that once magnetic-sector deflection was the way to do mass spectrometry."

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