Waters introduces new protein digest kits for LC-MS

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  • Published: Jan 20, 2016
  • Author: Jon Evans
  • Source: Waters Corporation
  • Suppliers: Waters Corporation
  • Channels: Sample Preparation / HPLC / Base Peak
thumbnail image: Waters introduces new protein digest kits for LC-MS

Waters Corporation has introduced a new line of Waters ProteinWorks digest kits that can simplify, accelerate and standardize the LC-MS quantification of proteins via the surrogate peptide approach.

The kits are an ideal solution for laboratories performing protein bioanalysis at innovator and biosimilar firms, contract research organizations, disease research centers, hospitals and university medical centers. The kits are expected to make it easier for biopharmaceutical scientists to deploy methods to contract organizations, as well as transfer methods from one laboratory to another.

“From our collaborations with scientists, it’s clear that a better approach to bioanalysis sample preparation is needed for therapeutic proteins. Today's methods are fraught with variability due to a lack of standardization,” said Mike Yelle, vice president, Waters Consumable Business Unit. “Our ProteinWorks kits simplify and standardize protein quantification workflows and shorten the time to precise and accurate results.”

ProteinWorks eXpress digest kits contain pre-measured, lot-traceable reagents, a 96-tube flexible sample collection module and easy-to-follow protocols that permit fast, reproducible digestion and accurate, sensitive protein quantification in both immune-purified and whole, non-immunopurified plasma and serum samples. The ProteinWorks product portfolio includes an optional, optimized µElution SPE kit and protocol designed to increase assay sensitivity, reduce matrix interferences and improve LC-MS system robustness.

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