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Classics in Spectroscopy

Date: Mar 11, 2009

Author: Stefan Berger, Dieter Sicker

The first book of its kind to describe the art of NMR using everyday examples. This textbook will not only fascinate students wanting to learn about the topic, but also those experienced analytical chemists who are still inspired by their profession. The contents provide for easy reading by using natural products that everyone knows, such as caffeine, backed by an attractive layout with many pictures to visualize the topics. In addition, an in-depth analytical part makes the book a valuable teaching...

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Mass Spectrometry in Drug Metabolism and Pharmacokinetics

Date: Jan 16, 2009

Author: Ragu Ramanathan

This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body,...

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Introduction to Proteomics

Date: Nov 7, 2008

Author: Agnieszka Kraj, Jerzy Silberring

Introduction to Proteomics is written by seasoned researchers with years of practical experience. In addition to comprehensive discussions of the basic concepts, techniques, and applications of the subject, the text also includes an extensive glossary and a chapter containing laboratory exercises and protocols. While mass spectrometry is central to proteomics, the book discusses all of the analytical techniques a student is likely to need when faced with real-world problems, such as sample preparation,...

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Handbook of GC/MS: Fundamentals and Applications

Date: Oct 22, 2008

Author: Hans-Joachim Hübschmann

This is the first comprehensive reference work for GC/MS now in its second edition. It offers broad coverage, from sample preparation to the evaluation of MS-Data, including library searches. Fundamentals, techniques, and applications are described. A large part of the book is devoted to numerous examples for GC/MS-applications in environmental, food, pharmaceutical and clinical analysis. These proven examples come from the daily practice of various laboratories. The book also features a glossary of terms...

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Fluorescence Methods and Applications: Spectroscopy, Imaging, and Probes

Date: Aug 8, 2008

Author: Otto S. Wolfbeis

This volume features papers on new spectroscopic methods and techniques, the development and application of fluorescent probes, and new techniques and applications of fluorescence imaging. Specific areas include the following: fluorescence lifetime, fluorescence (in vivo) imaging, time-resolved fluorescence, luminescence anisotropy, fluorescent (NMIR) labels, luminescent lanthanides, fluorescent sensors and probes, fluorescence microscopy, FRET, fluorescent nanoparticles and dots, high-throughput...

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Mass Spectra of Organic Compounds (SpecData)

Date: Jul 12, 2008

Author: Alexander Yarkov

Structural Diversity for Drug Discovery Mass Spectra of Organic Compounds contains 37,055 mass spectra of organic compounds. The data were acquired from quality control in combinatorial synthesis and cover a wide range of structure classes. The compounds are applied for screening purposes in drug discovery. Each record contains: Spectrum Chemical structure Chemical name Molecular formula Molecular weight (Nominal mass) Base peak Reference Measurement condition Verify Compound Coverage Labs...

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Even Electron Mass Spectrometry with Biomolecule Applications

Date: May 20, 2008

Author: Bryan M. Ham

In addition to the essential theoretical background and fundamental principles, this unique reference presents a detailed, step-by-step methodology for interpreting even electron mass spectrometry results. Specific chapters are devoted to: proteomics; biomolecule spectral interpretation of small molecules; biomolecule spectral interpretation of biological macromolecules; and MALDI-TOF-Postsource Decay (PSD). Chapters feature detailed examples, questions, and problems to help readers solidify their...

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Preclinical Development Handbook: ADME and Biopharmaceutical Properties

Date: Apr 29, 2008

Author: Shayne Cox Gad

A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for...

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GC/MS: A Practical User's Guide, 2nd Edition

Date: Apr 29, 2008

Author: Marvin McMaster

Updated and expanded, the classic guide to GC/MS helps chromatographers quickly learn to use this technique for analyzing and identifying compounds. After explaining the fundamentals, it discusses optimizing, tuning, using, and maintaining GC/MS equipment; explores advances in miniaturized and field-portable GC/MS systems and microfluidic components; and more. Complete with a CD-ROM, it covers applications in the environmental laboratory and in forensics, toxicology, and space science. This is the premier...

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Preclinical Development Handbook: Toxicology

Date: Apr 29, 2008

Author: Shayne Cox Gad

A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current...

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