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LC/MS Applications in Drug Development

Date: Mar 14, 2002

Author: Mike S. Lee

Breakthroughs in combinatorial chemistry and molecular biology, as well as an overall industry trend toward accelerated development, mean the rate of sample generation now far exceeds the rate of sample analysis in the pursuit of producing new and better pharmaceuticals. LC/MS is an analytical tool that helps the researcher identify the most promising sample early in the selection process, effectively creating a shortcut to finding new drugs. This book is the first to describe LC/MS applications within the...

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Encyclopedia of Imaging Science and Technology, 2 Volume Set

Date: Feb 27, 2002

Author: Joseph P. Hornak

This encyclopedia is the first to offer in-depth coverage of imaging science and technology from a diverse range of applications, techniques and fields of study. Today imaging is used by astronomers to map distant galaxies, oceanographers to map the sea floor, chemists to map the distribution of atoms on a surface, physicians to map the functionality of the brain and electrical engineers to map electromagnetic fields around power lines. With this encyclopedia, scientists, engineers and physicians can...

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Molecular Fluorescence

Date: Jan 15, 2002

Author: Bernard Valeur

Today, fluorescence spectroscopy is an important tool of investigation in many areas. In analytical sciences, its advantage is extremely high sensitivity and selectivity - even single molecules can be detected - and it achieves a high spatial resolution and time resolution in combination with microscopic techniques or laser techniques, respectively. In material sciences, this is used to study structure and dynamics of surfaces. Particularly in the areas of biochemistry and molecular genetics, fluorescence...

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Handbook of Vibrational Spectroscopy

Date: Dec 20, 2001

Author: John M. Chalmers, Peter Griffiths

THE DEFINITIVE RESOURCE The first truly comprehensive work on vibrational spectroscopy, providing a one-stop reference for infrared, near-infrared and Raman spectroscopy. AUTHORITATIVE, ... With contributions from acknowledged leaders in the field, the calibre of the editors and authors speaks for itself. Volume 1: Theory and Instrumentation Volume 2: Sampling Techniques Volume 3: Sample Characterization and Spectral Data Processing Volume 4: Applications in Industry, Materials and the Physical...

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Applications of Inorganic Mass Spectrometry

Date: Sep 3, 2001

Author: John R. de Laeter

Mass spectrometry is a powerful analytical technique used to identify unknown compounds, to quantify known materials, and to elucidate the structural and chemical properties of molecules. Inorganic mass spectrometry focuses on the analysis of metals and elements rather than organic compounds. Applications of Inorganic Mass Spectrometry describes developments in mass spectrometric instrumentation, together with applications in metrology, nuclear science, cosmochemistry, geoscience, environmental science,...

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Advances in Mass Spectrometry

Date: Jul 30, 2001

Author: Emilio Gelpi

This 15th volume of Advances in Mass Spectrometry brings together the key papers and abstracts from the 15th International Mass Spectrometry Conference. Attended by over 1100 scientists, this conference presented over 700 papers on all aspects of modern mass spectrometry. Coverage included the rapidly growing application areas in biochemisty, biology and medicine, as well as the fundamentals, instrumental and methodology developments of mass spectrometry which has all been brought together in one...

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Scanning Probe Microscopy and Spectroscopy: Theory, Techniques, and Applications, 2nd Edition

Date: Jan 3, 2001

Author: Dawn Bonnell

A practical introduction to basic theory and contemporary applications across a wide range of research disciplines Over the past two decades, scanning probe microscopies and spectroscopies have gained acceptance as indispensable characterization tools for an array of disciplines. This book provides novices and experienced researchers with a highly accessible treatment of basic theory, alongside detailed examples of current applications of both scanning tunneling and force microscopies and...

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Multivariate Analysis of Quality: An Introduction

Date: Dec 20, 2000

Author: Harald Martens, M. Martens

Data analysis is a vital part of science today, and in assessing quality, multivariate analysis is often necessary in order to avoid loss of essential information. Martens provides a powerful and versatile methodology that enables researchers to design their investigations and analyse data effectively and safely, without the need for formal statistical training. * Offers an introductory explanation of multivariate analysis by graphical 'soft modelling' * Minimises mathematics, providing all technical...

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Principles and Practice of Biological Mass Spectrometry

Date: Nov 8, 2000

Author: Chhabil Dass

A practical introduction to contemporary instrumentation, techniques, and applications This book provides professionals in the biological sciences with a solid basis in the fundamentals of contemporary mass spectrometry so that they can confidently choose and apply the best instrumentation and experimental approaches for their needs. The only single-volume guide of its kind, Principles and Practice of Biological Mass Spectrometry offers comprehensive coverage of the latest instrumentation, techniques, and...

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Shpol'skii Spectroscopy and Other Site-Selection Methods: Applications in Environmental Analysis, Bioanalytical Chemistry, and Chemical Physics

Date: Aug 22, 2000

Author: Cees Gooijer, Freek Ariese, Johannes W. Hofstraat

Recent technological breakthroughs, most notably in the field of lasers as well as detection and data processing, have made it possible to apply high-resolution molecular spectroscopy to such areas as environmental science, bioanalysis, and chemical physics. This book describes recent advances and applications of high-resolution molecular spectroscopy in low temperature solid matrices.

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