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Mass Spectrometry and Stable Isotopes in Nutritional and Pediatric Research

Date: Mar 24, 2017

Author: Henk Schierbeek

A guide for scientists, pediatricians and students involved in metabolic studies in pediatric research Addresses the availability of modern analytical techniques and how to apply these techniques in metabolic studies Covers the whole range of available mass spectrometric techniques used for metabolic studies including Stable Isotope Methodology Presents the relevance of mass spectrometry and stable isotope methodology in pediatric research covering applications in Nutrition, Obesity, Metabolic Disorders,...

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Oral Formulation Roadmap from Early Drug Discovery to Development

Date: Mar 24, 2017

Author: Elizabeth Kwong

Detailing formulation approaches by stage of discovery to early development, this book gives a “playbook” of practical and efficient strategies to formulate drug candidates with the least chance of failing in clinical development. •    Comes from contributing authors with experience developing formulations on the frontlines of the pharmaceutical industry•    Focuses on pre (or non-) clinical and early stage development, the phases where most compounds are...

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Interpretation of MS-MS Mass Spectra of Drugs and Pesticides

Date: Mar 17, 2017

Author: Wilfried M. A. Niessen, Ricardo A. Correa C.

Provides comprehensive coverage of the interpretation of LC–MS–MS mass spectra of 1300 drugs and pesticides Provides a general discussion on the fragmentation of even-electron ions (protonated and deprotonated molecules) in both positive-ion and negative-ion modes   This is the reference book for the interpretation of MS–MS mass spectra of small organic molecules  Covers related therapeutic classes of compounds such as drugs for cardiovascular diseases, psychotropic compounds,...

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Analytical Modeling of Solute Transport in Groundwater: Using Models to Understand the Effect of Natural Processes on Contaminant Fate and Transport

Date: Mar 17, 2017

Author: Mark Goltz, Junqi Huang

Teaches, using simple analytical models how physical, chemical, and biological processes in the subsurface affect contaminant transport Uses simple analytical models to demonstrate the impact of subsurface processes on the fate and transport of groundwater contaminants Includes downloadable modeling tool that provides easily understood graphical output for over thirty models Modeling tool and book are integrated to facilitate reader understanding Collects analytical solutions from many sources into a...

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The HPLC-Expert II: Optimizing the Benefits of HPLC/UHPLC

Date: Feb 22, 2017

Author: Stavros Kromidas

How can I use my HPLC/UHPLC equipment in an optimal way, where are the limitations of the technique? These questions are discussed in detail in the sequel of the successful "HPLC Expert" in twelve chapters written by experts in the respective fields. The topics encompass - complementary to the first volume - typical HPLC users' problems and questions such as gradient optimization and hyphenated techniques (LC-MS). An important key aspect of the book is UHPLC: For which analytical problem is it essential,...

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Chemical Analysis of Non-antimicrobial Veterinary Drug Residues in Food

Date: Dec 30, 2016

Author: Jack F. Kay, James D. MacNeil, Jian Wang

Provides a single-source reference for readers interested in the development of analytical methods for analyzing non-antimicrobial veterinary drug residues in food Provides a comprehensive set of information in the area of consumer food safety and international trade Covers general issues related to analytical quality control and quality assurance, measurement uncertainty, screening and confirmatory methods Details many techniques including nanotechnology and aptamer based assays covering current and...

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Analysis of Protein Post-Translational Modifications by Mass Spectrometry

Date: Dec 27, 2016

Author: John R. Griffiths, Richard D. Unwin

Covers all major modifications, including phosphorylation, glycosylation, acetylation, ubiquitination, sulfonation and and glycation Discussion of the chemistry behind each modification, along with key methods and references Contributions from some of the leading researchers in the field A valuable reference source for all laboratories undertaking proteomics, mass spectrometry and post-translational modification research

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Pharmaceutical Excipients: Properties, Functionality, and Applications in Research and Industry

Date: Dec 9, 2016

Author: Otilia M. Y. Koo

This book provides an overview of excipients, their functionalities in pharmaceutical dosage forms, regulation, and selection for pharmaceutical products formulation. It includes development, characterization methodology, applications, and up-to-date advances through the perspectives of excipients developers, users, and regulatory experts. Covers the sources, characterization, and harmonization of excipients: essential information for optimal excipients selection in pharmaceutical development Describes...

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Asymmetric Synthesis in Organophosphorus Chemistry: Synthetic Methods, Catalysis and Applications

Date: Nov 9, 2016

Author: Oleg I. Kolodiazhnyi

Authored by one of the leading experts in the field, this is the only comprehensive overview of chiral organophosphorus compounds, from asymmetric synthesis to catalysis and pharmacological applications. As such, this unique reference covers the chemical background as well as spectroscopical analysis of phosphorus compounds, and thoroughly describes all the various synthetic strategies for these substances. Metal-, organo- and biocatalyzed reactions for the introduction of phosphorus are explained as are...

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Crime Scene Management: Scene Specific Methods, 2nd Edition

Date: Oct 28, 2016

Author: Raul Sutton, Keith Trueman, Christopher Moran

Second edition of an established text on common procedures for the identification and processing of evidence at scenes of crime   Includes chapters on quality assurance and credibility of practices and processes issues surrounding major and complex crime  Forensic handling of mass fatalities Crime scene reconstruction and impact on evidence recovery processes

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