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Hydrogen Exchange Mass Spectrometry of Proteins

Date: Jul 3, 2015

Author: David Weis

Hydrogen exchange mass spectrometry is widely recognized for its ability to probe the structure and dynamics of proteins. The application of this technique is becoming widespread due to its versatility for providing structural information about challenging biological macromolecules such as antibodies, flexible proteins and glycoproteins. Although the technique has been around for 25 years, this is the first definitive book devoted entirely to the topic. Hydrogen Exchange Mass Spectrometry of Proteins:...

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Mass Spectrometry for the Analysis of Pesticide Residues and their Metabolites

Date: Jun 2, 2015

Author: Despina Tsipi, Helen Botitsi, Anastasios Economou

Provides an overview of the use of mass spectrometry (MS) for the analysis of pesticide residues and their metabolites. Presents state of the-art MS techniques for the identification of pesticides and their transformation products in food and environment Covers important advances in MS techniques including MS instrumentation and chromatographic separations (e.g. UPLC, HILIC, comprehensive GCxGC) and applications Illustrates the main sample preparation techniques (SPE, QuEChERS, microextraction) used in...

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Analyzing Biomolecular Interactions by Mass Spectrometry

Date: May 15, 2015

Author: Jeroen Kool, Wilfried M. A. Niessen

This monograph reviews all relevant technologies based on mass spectrometry that are used to study or screen biological interactions in general. Arranged in three parts, the text begins by reviewing techniques nowadays almost considered classical, such as affinity chromatography and ultrafiltration, as well as the latest techniques. The second part focusses on all MS-based methods for the study of interactions of proteins with all classes of biomolecules. Besides pull down-based approaches, this section...

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Pharmaceutical Amorphous Solid Dispersions

Date: May 13, 2015

Author: Ann Newman

Providing a roadmap from early to late stages of drug development, this book overviews amorphous solid dispersion technology – a leading platform to deliver poorly water soluble drugs, a major hurdle in today’s pharmaceutical industry. • Helps readers understand amorphous solid dispersions and apply techniques to particular pharmaceutical systems • Covers physical and chemical properties, screening, scale-up, formulation, drug product manufacture, intellectual property,...

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Mass Spectra of Designer Drugs 2015

Date: May 13, 2015

Author: Peter Rosner

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Mass Spectra of Designer Drugs 2015

Date: Mar 18, 2015

Author: Peter Rosner

Compounds classifed as "Designer Drugs" have been synthesized for several decades. This is not a precise scientific term and should only be applied to those drugs that are synthesized from common chemicals and skillfully marketed under attractive, exotic names, often to skirt existing laws.Because many designer drugs are novel or designed to evade detection, they can be overlooked or difficult to detect or characterize. The last two decades have seen a proliferation of such substances, such that keeping...

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Handbook of GC / MS: Fundamentals and Applications, 3rd Edition

Date: Feb 11, 2015

Author: Hans-Joachim Hubschmann

The only comprehensive reference on this popular and rapidly developing technique provides a detailed overview, ranging from fundamentals to applications, including a section on the evaluation of GC-MS analyses. As such, it covers all aspects, including the theory and principles, as well as a broad range of real-life examples taken from laboratories in environmental, food, pharmaceutical and clinical analysis. It also features a glossary of approximately 300 terms and a substance index that facilitates...

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Structure Elucidation in Organic Chemistry

Date: Jan 28, 2015

Author: Maria-Magdalena Cid, Jorge Bravo

Intended for advanced readers, this is a review of all relevant techniques for structure analysis in one handy volume. As such, it provides the latest knowledge on spectroscopic and related techniques for chemical structure analysis, such as NMR, optical spectroscopy, mass spectrometry and X-ray crystallography, including the scope and limitation of each method. As a result, readers not only become acquainted with the techniques, but also the advantages of the synergy between them. This enables them to...

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Handbook of Petroleum Product Analysis, 2nd Edition

Date: Jan 16, 2015

Author: James G. Speight

Introduces the reader to the production of the products in a refinery • Introduces the reader to the types of test methods applied to petroleum products, including the need for specifications • Provides detailed explanations for accurately analyzing and characterizing modern petroleum products • Rewritten to include new and evolving test methods • Updates on the evolving test methods and new test methods as well as the various environmental regulations...

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NIST / EPA / NIH Mass Spectral Library 2014 Upgrade

Date: Dec 12, 2014

Author: NIST, Wiley Technology

NIST/EPA/NIH 2014 Mass Spectral Library (UPGRADE) is a trusted source of mass spectral data and software tools. The newest edition contains an expansion of the main EI library as well as significant improvements in the underlying MS Search software (2.2). Protect Your InvestmentWiley's NIST 2014 is the most comprehensive available, with more manufacturer formats on one disc than any other source. This helps ensure transportability when switching instruments or manufacturers, and takes the guesswork...

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