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Lipidomics and metabolomics: Simultaneous analysis

Date: Jan 21, 2019

Author: Steve Down

A new workflow comprising parallel HILIC and RPLC separations permits simultaneous lipidomics and metabolomics analyses in one LC/MS run without affecting the throughput, providing both compound identification and quantification.

Read More thumbnail image: Lipidomics and metabolomics Simultaneous analysis

Journal Highlight: Newborn screening for 3‐hydroxy‐3‐methylglutaric aciduria using direct analysis in real‐time mass spectrometry

Date: Jan 16, 2019

Author: spectroscopyNOW

A novel method utilizing ambient thermal desorption ionization with a direct analysis in real‐time source integrated with mass spectrometry (DART-MS) has been established and applied to the rapid analysis of 3‐hydroxy‐3‐methylglutaric acid in neonatal urine.

Read More thumbnail image: Journal Highlight Newborn screening for 3hydroxy3methylglutaric aciduria using direct analysis in realtime mass spectrometry

Sugars from space: Meteorite sources supported

Date: Jan 1, 2019

Author: Steve Down

Deoxysugars, which are building blocks of life, have been formed in the lab under conditions that simulate the astrophysical environment of ices, supporting their formation in space, say NASA researchers, who also found deoxysugar derivatives in meteorites to reinforce the connection.

Read More thumbnail image: Sugars from space Meteorite sources supported

Ginseng farming methods: Organic acid indicators

Date: Dec 18, 2018

Author: Steve Down

Organic acid profiling by GC/MS can distinguish conventionally farmed ginseng from that farmed in a pesticide-free environment, say South Korean researchers, who used star pattern recognition for data evaluation.

Read More thumbnail image: Ginseng farming methods Organic acid indicators

Journal Highlight: Volatile compounds profiling by using proton transfer reaction–time of flight–mass spectrometry (PTR‐ToF‐MS). The case study of dark chocolates organoleptic differences

Date: Dec 13, 2018

Author: spectroscopyNOW

Various direct injection mass spectrometry methods used for the analysis of foodstuffs have been briefly reviewed, emphasising proton transfer reaction mass spectrometry (PTR‐MS), and a case study for classifying dark chocolates by PTR-ToFMS has been presented.

Read More thumbnail image: Journal Highlight Volatile compounds profiling by using proton transfer reactiontime of flightmass spectrometry PTRToFMS_ The case study of dark chocolates organoleptic differences

Journal Highlight: Identification of potential metabolic biomarkers in Yin deficiency syndrome using LC–MS

Date: Dec 5, 2018

Author: spectroscopyNOW

A UPLC–MS metabolomics method has been developed to identify potential biomarkers for Yin deficiency syndrome, a common sub‐health state with complex causes.

Read More thumbnail image: Journal Highlight Identification of potential metabolic biomarkers in Yin deficiency syndrome using LCMS

Aquatic pharmaceutical pollution: Food web accumulation

Date: Dec 1, 2018

Author: Steve Down

The levels of 98 common pharmaceuticals have been measured in spiders and invertebrates living along the edges of six streams in Melbourne, Australia, suggesting that creatures at the top of the food web, like platypus and brown trout, could be exposed to high doses in their diets.

Read More thumbnail image: Aquatic pharmaceutical pollution Food web accumulation

Metabolic tissue imaging: Ambient mass spectrometry for global coverage

Date: Nov 15, 2018

Author: Steve Down

A wide range of metabolites have been mapped in tissue using ambient mass spectrometry, which could help to divulge molecular processes and pathological mechanisms and lead to the discovery of new biomarkers.

Read More thumbnail image: Metabolic tissue imaging Ambient mass spectrometry for global coverage

Journal Highlight: Analyte‐substrate interactions at functionalized tip‐electrospray ionization mass spectrometry: Molecular mechanisms and applications

Date: Nov 5, 2018

Author: spectroscopyNOW

Model mixtures and functionalized tips have been employed to investigate the molecular mechanism of the analyte‐substrate interactions in tip electrospray ionization mass spectrometry.

Read More thumbnail image: Journal Highlight Analytesubstrate interactions at functionalized tipelectrospray ionization mass spectrometry Molecular mechanisms and applications

Insulin analysis: Dried blood spots

Date: Nov 2, 2018

Author: Steve Down

An LC/MS method has been developed for the analysis of insulin and its synthetic analogues from dried blood spots, which could be applied to doping control, forensic and pharmacological fields.

Read More thumbnail image: Insulin analysis Dried blood spots
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