Base Peak / Ezine
Lung cancer blowout
Date: May 15, 2010
Author: Steve Down
The levels of certain aldehydes in the breath are indicative of lung cancer, say researchers in Germany, who measured their levels by GC/MS following SPME on-fibre derivatisation. The findings may lead to a non-invasive test for lung malignancies.
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Development of a high sensitivity bioanalytical method for alprazolam using ultra-performance liquid chromatography/tandem mass spectrometry
Date: May 10, 2010
Author:
A rapid assay for the benzodiazepine alprazolam in rat plasma using sub-2 µm particle LC and tandem quadrupole mass spectrometry gave a limit of quantification using SPE of 1.0 pg/mL.
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Feather duster
Date: May 1, 2010
Author: Steve Down
The feathers of the endangered California condor hold a history of exposure to lead along their length, in a similar manner to drugs of abuse in hair, say US researchers, so that they can be used for long-term monitoring of lead exposure in the wild.
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Catch your breath
Date: Apr 15, 2010
Author: Steve Down
The levels of ethanol and its metabolites have been measured simultaneously in real time in the breath exhaled through the noses and mouths of two volunteers by non-invasive sampling and SIFT MS, to give detailed information on the kinetics of ethanol decay in the blood stream.
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The use of in vitro technologies coupled with high resolution accurate mass LC-MS for studying drug metabolism in equine drug research
Date: Apr 12, 2010
Author:
Equine liver/lung microsomes/S9 tissue fractions were used to study the phase I metabolism of eight drugs of relevance to equine drug surveillance using accurate mass LC/MS, to reduce the dependence on in vivo studies.
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PCBs from scrap paper
Date: Apr 1, 2010
Author: Steve Down
Carelessly discarded newspapers and magazines contribute to the high levels of a particular PCB in river water, say US researchers. In some cases, the levels of this compound alone exceed the recommended total maximum daily load for the sum of all PCBs.
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Hair equals bone for ancient diet research
Date: Mar 15, 2010
Author: Steve Down
A new LC/MS method has been developed for measuring the delta-13C values of amino acids extracted from hair and bone. Comparison of the results indicated that hair could be an alternative medium for analysing samples from archaeological individuals for dietary reconstruction.
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The ion funnel: Theory, implementations, and applications
Date: Mar 8, 2010
Author:
Improvements in the fundamental understanding of ion motion in ion funnels, the evolution in its implementations, and the applications of the ion funnel have been reviewed.
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Paper power
Date: Mar 1, 2010
Author: Steve Down
The scope of paper spray ionisation, a new ambient ionisation technique, has been explored by its inventors. It can detect small and large molecules at ppm levels and presents a genuine opportunity for developing point-of-care applications.
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Scented human barcode
Date: Feb 15, 2010
Author: Steve Down
Humans can be identified from the ratios of characteristic scent compounds emitted from their hands, say US scientists, who have devised a human barcode based on the relative concentrations of the primary odour compounds.
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