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An introduction to LC/MS instrumentation applied in plant metabolomic analyses

Date: Feb 8, 2010

Author:

This review sets out to introduce the background and update the reader upon LC, high performance (HP)LC and UHPLC, as well as the large range of MS instruments that are being applied in current plant metabolomic studies.

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Remote pooling of trihalomethanes

Date: Feb 1, 2010

Author: Steve Down

The daily rhythm of disinfection by-products in a public swimming pool is linked to the opening and closing times, say Danish scientists, who measured their levels in real time with an on-site membrane inlet mass spectrometer.

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Divining dirty water

Date: Jan 15, 2010

Author: Steve Down

A broad range of pollutants has been measured in environmental water by an optimised GC/MS technique with large volume injection, after a step by step analysis of the individual processes involved.

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Electrospray: From ions in solution to ions in the gas phase, what we know now

Date: Jan 11, 2010

Author:

The various processes involved in the conversion of ions present in the solution to ions in the gas phase in electrospray and nanospray mass spectrometry are discussed in detail.

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Space dust spectroscopy

Date: Jan 4, 2010

Author: Steve Down

The hyper-velocity impacts of organic micrograins have been studied by mass spectrometry in a dust accelerator to determine the species produced. The results are important for the in situ identification of organic compounds in space dust.

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Well spotted

Date: Dec 15, 2009

Author: Steve Down

The prenatal exposure of newborns to perfluoroalkyl chemicals has been assessed by LC/MS using dried blood spots collected routinely after births in the USA. Almost 100 babies tested had ppm levels of the chemicals in their blood.

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Detection of the arylpropionamide-derived selective androgen receptor modulator (SARM) S-4 (Andarine) in a black-market product

Date: Dec 7, 2009

Author:

The SARM drug candidate andarine, which is available over the Internet, was detected for the first time, using an LC/MS method. The performance-enhancing qualities and the black-market availability of SARMs makes them viable targets for misuse in the athletic community.

Read More thumbnail image: Detection of the arylpropionamide-derived selective androgen receptor modulator SARM S-4 Andarine in a black-market product

Collaring collagen for mammalian identification

Date: Dec 1, 2009

Author: Steve Down

Collagen from bone fragments has been used to identify the mammalian species by mass spectrometry, say UK scientists, who applied the method successfully to modern and archaeological bone, as well as rendered meat and bone meal.

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The past is coming back to haunt us

Date: Nov 15, 2009

Author: Steve Down

The accelerated melting of an Alpine glacier induced by global warming is releasing trapped persistent organic chemicals into local lakes at historically high rates, say Swiss researchers.

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Generic sample preparation and dual polarity LC-TOFMS for high-throughput screening in doping analysis

Date: Nov 9, 2009

Author:

A comprehensive screening method for doping agents in human urine is presented, based on SPE and liquid chromatography-time-of-flight mass spectrometry, covering most of the compound groups in the WADA list of prohibited substances.

Read More thumbnail image: Generic sample preparation and dual polarity LC-TOFMS for high-throughput screening in doping analysis
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