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Polarity changes: Simultaneous positive and negative modes in DESI

Date: Apr 15, 2013

Author: Steve Down

Danish scientists have introduced a dual-mode imaging system for desorption ionisation mass spectrometry, in which images can be acquired in positive and negative mode simultaneously.

Read More thumbnail image: Polarity changes Simultaneous positive and negative modes in DESI

Journal Highlight: Soft ionization mass spectroscopy: Insights into the polymerization mechanism

Date: Apr 8, 2013

Author: spectroscopyNOW

This review is focused on the use of soft ionization mass spectroscopy to characterize the products of polymerization/degradation reactions thereby yielding mechanistic information.

Read More thumbnail image: Journal Highlight Soft ionization mass spectroscopy Insights into the polymerization mechanism

Chocolate threats: Carcinogenic PAHs

Date: Apr 1, 2013

Author: Steve Down

Several polycyclic aromatic hydrocarbons have been determined in chocolate by GC/MS following a specially devised SPME procedure, giving a more sensitive method than an HPLC procedure developed in 2012 by the same research group.

Read More thumbnail image: Chocolate threats Carcinogenic PAHs

Gut instinct: Stem cell reactions

Date: Apr 1, 2013

Author: David Bradley

In research funded by Great Ormond Street Hospital Children's Charity and with support from the Fondazione Citta della Speranza, researchers have demonstrated that stem cells taken from amniotic fluid can be used to restore gut structure and function following intestinal damage in rodents. The new work published in the journal Gut uses magnetic resonance imaging and could pave the way to a new form of cell therapy that is able to reverse serious damage caused by inflammation in the intestines of babies.

Read More thumbnail image: Gut instinct Stem cell reactions

Keeping your nerve: VX in drinking water

Date: Mar 15, 2013

Author: Steve Down

The nerve agent VX has been determined in drinking water by a high-throughput LC/MS method combined with special treatment to prevent it from decomposing before analysis.

Read More thumbnail image: Keeping your nerve VX in drinking water

Journal Highlight: Investigations of chemical warfare agents and toxic industrial compounds with proton-transfer-reaction mass spectrometry for a real-time threat monitoring scenario

Date: Mar 11, 2013

Author: spectroscopyNOW

Chemical warfare agents and toxic industrial compounds have been studied by high-resolution PTR-TOFMS to identify key product ions and their intensities with which to develop a low-resolution PTR-MS system for detecting threat agents in the atmosphere.

Read More thumbnail image: Journal Highlight Investigations of chemical warfare agents and toxic industrial compounds with proton-transfer-reaction mass spectrometry for a real-time threat monitoring scenario

Two are better than one: Dual electrosprays for desorbed samples in ambient mass spectrometry

Date: Mar 1, 2013

Author: Steve Down

A laser desorption ambient mass spectrometry system with two post-desorption sprayers gives the flexibility to carry out different procedures on the same sample during the same experiment, rapidly switching spectra.

Read More thumbnail image: Two are better than one Dual electrosprays for desorbed samples in ambient mass spectrometry

Safety of implantable medical devices: Antioxidant breakdown products classified

Date: Feb 15, 2013

Author: Steve Down

Components related to antioxidants that leach out of implantable medical devices, like artificial joint inserts, have been identified and measured by GC/MS to check their safety credentials.

Read More thumbnail image: Safety of implantable medical devices Antioxidant breakdown products classified

Journal Highlight: Early synthetic dyes – a challenge for tandem mass spectrometry

Date: Feb 11, 2013

Author: spectroscopyNOW

Early yellow synthetic dyes from silk fibres taken from the 1930 spring colour palette of the Lyon Dyers’ Guild (La Chambre Syndicale des Teinturiers) have been identified, primarily by electrospray MS/MS.

Read More thumbnail image: Journal Highlight Early synthetic dyes  a challenge for tandem mass spectrometry

Tipping point: Wooden toothpicks for ambient ionisation of illegal drugs

Date: Feb 1, 2013

Author: Steve Down

Ketamine and its major metabolite norketamine have been measured in urine and oral fluid by ambient electrospray mass spectrometry using a wooden toothpick as the sample holder.

Read More thumbnail image: Tipping point Wooden toothpicks for ambient ionisation of illegal drugs
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