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Biofluid identity: Forensic evidence

Date: Jun 15, 2018

Author: Steve Down

Human body fluids collected at crime scenes can be classified from their constituent proteins in a single mass spectrometric experiment that can be combined with DNA analysis for suspect identification.

Read More thumbnail image: Biofluid identity Forensic evidence

Journal Highlight: The ongoing evolution of laser desorption/ionization mass spectrometry: Some observations on current trends and future directions

Date: Jun 11, 2018

Author: spectroscopyNOW

Some of the numerous, but scattered reports on novel laser desorption/ionization strategies have been reviewed with an emphasis on modified sample support substrates and plates and their potential to markedly enhance the utility of LDI‐MS.

Read More thumbnail image: Journal Highlight The ongoing evolution of laser desorptionionization mass spectrometry Some observations on current trends and future directions

Very volatile organic compounds: Indoor air testing

Date: Jun 1, 2018

Author: Steve Down

A new thermal desorption-GC/MS procedure has been developed by scientists in Germany for the determination of very volatile organic compounds in indoor air, but it must be supplemented by at least two other methods to include the full range of compounds.

Read More thumbnail image: Very volatile organic compounds Indoor air testing

Emerging perfluorinated pollutants: Mass spectrometric solution

Date: May 15, 2018

Author: Steve Down

A mass spectrometric method has been developed for measuring perfluoroether carboxylic acids in water that can be applied to exposure monitoring of fluorinated industrial contaminants.

Read More thumbnail image: Emerging perfluorinated pollutants Mass spectrometric solution

Journal Highlight: Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants

Date: May 7, 2018

Author: spectroscopyNOW

An overview on the latest developments in mass spectrometry and its hyphenated technique and their applications for the comprehensive analysis of medicinal plants has concluded that the technique will remain invaluable for high‐throughput or multi‐dimensional analysis of medicinal plants.

Read More thumbnail image: Journal Highlight Recent development in mass spectrometry and its hyphenated techniques for the analysis of medicinal plants

The force of Orbitrap can thwart doping from the dark side of sport

Date: May 2, 2018

Author: Ryan De Vooght-Johnson

The use of anabolic steroids by athletes for doping purposes remains a serious problem, but existing analytical methods tend to give poor detection of some steroids, particularly novel ‘designer steroids’, which are often not found in databases. Researchers from the Federal University of Rio de Janeiro and Thermo Fisher (Austin, Texas) devised a new method using GC and an Orbitrap mass spectrometer to detect both known and novel anabolic steroids, along with other doping compounds.

Read More thumbnail image: The force of Orbitrap can thwart doping from the dark side of sport

Heart testing: Improving the troponin I assay

Date: May 1, 2018

Author: Steve Down

A novel mass spectrometric assay for cardiac troponin I improves upon current immunoassays which give variable results from type to type and facilitates use of troponin in clinical care.

Read More thumbnail image: Heart testing Improving the troponin I assay

Drug binding: Optical interferometry-mass spectrometry system

Date: Apr 15, 2018

Author: Steve Down

A novel system for assessing drug-protein binding that combines nanopore optical interferometry with mass spectrometry has been developed to accelerate the drug discovery process.

Read More thumbnail image: Drug binding Optical interferometry-mass spectrometry system

Journal Highlight: Unprecedented ionization processes in mass spectrometry provide missing link between ESI and MALDI

Date: Apr 9, 2018

Author: spectroscopyNOW

Intact, highly‐charged protein ions have been formed on high vacuum TOF mass spectrometers in linear and reflectron modes by effective matrix removal from sample surfaces and charged clusters, suggesting mechanistic links to traditional ionization methods of electrospray ionization and matrix‐assisted laser desorption/ionization.

Read More thumbnail image: Journal Highlight Unprecedented ionization processes in mass spectrometry provide missing link between ESI and MALDI

Advanced forensic fingerprinting: Imaging from cyanoacrylate-fumed prints

Date: Apr 1, 2018

Author: Steve Down

The classical forensic fingerprint technique of cyanoacrylate fuming is compatible with mass spectrometry imaging, say US researchers, who used an orbitrap system rather than time-of-flight techniques to improve performance and detect endogenous and exogenous substances.

Read More thumbnail image: Advanced forensic fingerprinting Imaging from cyanoacrylate-fumed prints
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