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Journal Highlight: Volatile compounds profiling by using proton transfer reaction–time of flight–mass spectrometry (PTR‐ToF‐MS). The case study of dark chocolates organoleptic differences

Date: Dec 13, 2018

Author: spectroscopyNOW

Various direct injection mass spectrometry methods used for the analysis of foodstuffs have been briefly reviewed, emphasising proton transfer reaction mass spectrometry (PTR‐MS), and a case study for classifying dark chocolates by PTR-ToFMS has been presented.

Read More thumbnail image: Journal Highlight Volatile compounds profiling by using proton transfer reactiontime of flightmass spectrometry PTRToFMS_ The case study of dark chocolates organoleptic differences

Journal Highlight: Identification of potential metabolic biomarkers in Yin deficiency syndrome using LC–MS

Date: Dec 5, 2018

Author: spectroscopyNOW

A UPLC–MS metabolomics method has been developed to identify potential biomarkers for Yin deficiency syndrome, a common sub‐health state with complex causes.

Read More thumbnail image: Journal Highlight Identification of potential metabolic biomarkers in Yin deficiency syndrome using LCMS

Aquatic pharmaceutical pollution: Food web accumulation

Date: Dec 1, 2018

Author: Steve Down

The levels of 98 common pharmaceuticals have been measured in spiders and invertebrates living along the edges of six streams in Melbourne, Australia, suggesting that creatures at the top of the food web, like platypus and brown trout, could be exposed to high doses in their diets.

Read More thumbnail image: Aquatic pharmaceutical pollution Food web accumulation

Metabolic tissue imaging: Ambient mass spectrometry for global coverage

Date: Nov 15, 2018

Author: Steve Down

A wide range of metabolites have been mapped in tissue using ambient mass spectrometry, which could help to divulge molecular processes and pathological mechanisms and lead to the discovery of new biomarkers.

Read More thumbnail image: Metabolic tissue imaging Ambient mass spectrometry for global coverage

Journal Highlight: Analyte‐substrate interactions at functionalized tip‐electrospray ionization mass spectrometry: Molecular mechanisms and applications

Date: Nov 5, 2018

Author: spectroscopyNOW

Model mixtures and functionalized tips have been employed to investigate the molecular mechanism of the analyte‐substrate interactions in tip electrospray ionization mass spectrometry.

Read More thumbnail image: Journal Highlight Analytesubstrate interactions at functionalized tipelectrospray ionization mass spectrometry Molecular mechanisms and applications

Insulin analysis: Dried blood spots

Date: Nov 2, 2018

Author: Steve Down

An LC/MS method has been developed for the analysis of insulin and its synthetic analogues from dried blood spots, which could be applied to doping control, forensic and pharmacological fields.

Read More thumbnail image: Insulin analysis Dried blood spots

Nerve agent detection: Derivatisation for paper spray mass spectrometry

Date: Oct 15, 2018

Author: Steve Down

The G-series chemical warfare agents have been analysed by flowing vapour samples through a treated cartridge to trap and derivatise them for paper spray mass spectrometry.

Read More thumbnail image: Nerve agent detection Derivatisation for paper spray mass spectrometry

Journal Highlight: Novel ionization processes for use in mass spectrometry: 'Squeezing' nonvolatile analyte ions from crystals and droplets

Date: Oct 8, 2018

Author: spectroscopyNOW

This perspective examines the mechanisms, instrumentation and applications of matrix-assisted ionisation, laserspray ionization and solvent-assisted ionization with small portable mass spectrometers, (ultra)high resolution MS, automation, ion mobility spectrometry, MS/MS using advanced CID and/or advanced fragmentation technology such as electron transfer dissociation.

Read More thumbnail image: Journal Highlight Novel ionization processes for use in mass spectrometry Squeezing nonvolatile analyte ions from crystals and droplets

MS/MS measures metabolites from marijuana

Date: Oct 3, 2018

Author: Ryan De Vooght-Johnson

Detection of cannabinoids in hair is a common method of drug testing, but improved chromatographic techniques are needed to analyse cannabinoid metabolites, which tend to be present at very low levels. Scientists from the University of Cologne and Gerstel GmbH (Mülheim, Germany) developed a new GC-MS/MS to quantify a range of cannabinoids, including metabolite compounds.

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Hospital air: Chemical and microbiological assessment

Date: Oct 1, 2018

Author: Steve Down

Indoor air of two French hospitals contains the same types of contaminants, including volatile organic compounds from inside and outside the buildings, microorganisms and particulates. The findings will help to establish indoor air quality recommendations for healthcare facilities.

Read More thumbnail image: Hospital air Chemical and microbiological assessment
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