Base Peak / Ezine
Journal Highlight: Applications of mass spectrometry to metabolomics and metabonomics: Detection of biomarkers of aging and of age-related diseases
Date: Jan 16, 2012
Author:
The application of metabolomics to aging research is reviewed for two primary audiences: mass spectrometrists interested in applying their technical knowledge to unanswered questions in the aging field, and gerontologists interested in expanding their knowledge of both mass spectrometry and the most recent advances in aging-related metabolomics.
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Expanding doping detection: Screening for carbohydrate-based plasma volume expanders
Date: Jan 15, 2012
Author: Steve Down
The plasma volume expanders mannitol, dextran and hydroxyethyl starch, which are on the WADA prohibited list as masking agents, have been determined in urine by a mass spectrometric method. The procedure has been validated to WADA requirements for accredited laboratories.
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Forgeries foiled: EASI mass spectrometry identifies falsified vehicle registration documents
Date: Jan 5, 2012
Author: Steve Down
Forged Brazilian vehicle documents have been detected by ambient mass spectrometry due to the presence of a stabiliser found in printing ink that is absent from genuine documents.
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Banged to rights: Firearms distinguished using gunshot residues on fabrics
Date: Dec 15, 2011
Author: Steve Down
Gunshot residues on different types of fabrics have been analysed by high resolution mass spectrometry and the elemental data displayed on ternary graphs to reveal the type of weapon that was fired. The method could provide vital clues in forensic investigations where the firearm has not been recovered.
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Journal Highlight: The pivotal role of mass spectrometry in determining the presence of chemical contaminants in food raw materials
Date: Dec 12, 2011
Author:
The contribution and potential of mass spectrometry-based techniques, with and without chromatographic coupling, to ensure the absence of chemical contaminants in food-based products has been reviewed.
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False negatives in food: High resolution mass spectrometry sorts analytes from interferents
Date: Dec 1, 2011
Author: Steve Down
A common food contaminant which could not be confirmed in many foods by tandem mass spectrometry due to a coeluting compound has been analysed successfully using high resolution mass spectrometry, preventing the occurrence of potentially harmful false negatives.
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The pressure is on: Imaging mass spectrometry for bedsore profiles
Date: Nov 15, 2011
Author: Steve Down
The protein and lipid compositions of pressure ulcers have been visualised by imaging mass spectrometry to give a much-needed view of the molecular status of these chronic wounds that could lead to a prognostic test of their reparative status.
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Journal Highlight: Simultaneous determination nucleosides in marine organisms using ultrasound-assisted extraction followed by HILIC-electrospray ionization TOFMS
Date: Nov 7, 2011
Author:
Ultrasound-assisted extraction followed by hydrophilic interaction chromatography and electrospray ionization time-of-flight mass spectrometry has been applied to the simultaneous determination of 16 nucleosides and nucleobases in medicinal extracts of various marine organisms.
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Cleaning up: Fabrics retain remnants of dry cleaning fluid
Date: Nov 1, 2011
Author: Steve Down
The dry cleaning fluid perchloroethylene is retained in fabrics for up to seven days after cleaning, presenting a potential health risk by inhalation and dermal absorption and warranting further studies on exposure of this potential carcinogen.
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Sweet tracer: Sucralose in drinking water is a marker for human activity
Date: Oct 15, 2011
Author: Steve Down
The majority of purified drinking water streams leaving domestic wastewater treatment plants in the US are contaminated with sucralose, suggesting that this artificial sweetener can be used as a marker for anthropogenic input in source and drinking water.
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