Base Peak / Ezine
Journal Highlight: Guidelines and recommended terms for expression of stable-isotope-ratio and gas-ratio measurement results
Date: Oct 9, 2011
Author:
To minimize confusion in the expression of measurement results of stable isotope and gas-ratio measurements, recommendations based on publications of the Commission on Isotopic Abundances and Atomic Weights of the International Union of Pure and Applied Chemistry (IUPAC) are presented.
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Tumour trials: Real-time boundary demarcation by ultrasonic aspiration and ambient mass spectrometry
Date: Oct 1, 2011
Author: Steve Down
Brain tissue can be analysed in real time in a surgical setting by a combination of ultrasonic aspiration and sonic spray mass spectrometry, raising the possibility of detecting tumour margins in the operating theatre without the addition of chemical tags. The procedure can easily be extended to other tissue types.
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Breath test boundaries: Food-borne interferents in test for invasive aspergillosis
Date: Sep 15, 2011
Author: Steve Down
Several foods and drinks are sources of 2-pentylfuran, a potential breath test marker for invasive aspergillosis, new research has shown. Patient diet should be taken into account to avoid false positive results if the GC/MS-based test is adopted.
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Journal Highlight: Synthesis, characterisation, and mass spectrometric detection of a pegylated EPO-mimetic peptide for sports drug testing purposes
Date: Sep 12, 2011
Author:
A pegylated EPO-mimetic peptide simulating the lead drug candidate peginesatide was synthesised as a model compound and characterised by gel electrophoresis, MALDI MS and LC/ESI-MS/MS after proteolytic digestion, to develop a method for detection in plasma.
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Terror trap: Walkthrough portal for explosives screening
Date: Sep 1, 2011
Author: Steve Down
A walkthrough portal for detecting traces of explosives on passengers based on APCI mass spectrometry and a novel linear ion trap has been demonstrated in Japan with triacetone triperoxide, one of the favoured explosives used by terrorists.
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A new LESA life: screening food surfaces for pesticides by liquid extraction surface analysis
Date: Aug 15, 2011
Author: Steve Down
Pesticides on food surfaces at levels 20-fold lower than current EPA tolerance levels have been detected by mass spectrometry following automated sampling by liquid extraction surface analysis, providing a rapid screening procedure for food supplies.
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Journal Highlight: Investigation of the afterglow time regime in pulsed radiofrequency glow discharge time-of-flight mass spectrometry
Date: Aug 8, 2011
Author:
The pulsed power operation mode of a radiofrequency glow discharge time-of-flight mass spectrometer was investigated for several ions, in terms of intensity profiles along each pulse period, with particular attention to the plateau and transient afterglow regions.
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Orange legacy: High levels of PCDDs in Vietnamese breast milk from historical Agent Orange spraying
Date: Aug 1, 2011
Author: Steve Down
Dioxins present in Agent Orange, the defoliant sprayed during the Vietnam War, remain at elevated levels in the milk of Vietnamese nursing mothers residing in the contaminated areas more than 40 years later, with major health implications for the feeding infants.
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Increasing ions: solvent-assisted inlet ionisation boosts sensitivity
Date: Jul 15, 2011
Author: Steve Down
A novel form of inlet ionisation mass spectrometry for samples in solution has been demonstrated by scientists in the USA. The technique differs from atmospheric pressure ionisation by transporting the solution to the vacuum inlet via a heated capillary in which ionisation occurs, effectively reducing ion losses and increasing sensitivity.
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Journal Highlight: Development and validation of LC-HRMS and GC-NICI-MS methods for stereoselective determination of MDMA and its phase I and II metabolites in human urine
Date: Jul 11, 2011
Author:
Three mass spectrometric methods involving LC/MS and GC/MS were derived and validated for evaluating the stereoselective elimination of phase I and phase II metabolites of MDMA in human urine.
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