Base Peak / Ezine
Journal Highlight: The pivotal role of mass spectrometry in determining the presence of chemical contaminants in food raw materials
Date: Dec 12, 2011
Author:
The contribution and potential of mass spectrometry-based techniques, with and without chromatographic coupling, to ensure the absence of chemical contaminants in food-based products has been reviewed.
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False negatives in food: High resolution mass spectrometry sorts analytes from interferents
Date: Dec 1, 2011
Author: Steve Down
A common food contaminant which could not be confirmed in many foods by tandem mass spectrometry due to a coeluting compound has been analysed successfully using high resolution mass spectrometry, preventing the occurrence of potentially harmful false negatives.
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The pressure is on: Imaging mass spectrometry for bedsore profiles
Date: Nov 15, 2011
Author: Steve Down
The protein and lipid compositions of pressure ulcers have been visualised by imaging mass spectrometry to give a much-needed view of the molecular status of these chronic wounds that could lead to a prognostic test of their reparative status.
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Journal Highlight: Simultaneous determination nucleosides in marine organisms using ultrasound-assisted extraction followed by HILIC-electrospray ionization TOFMS
Date: Nov 7, 2011
Author:
Ultrasound-assisted extraction followed by hydrophilic interaction chromatography and electrospray ionization time-of-flight mass spectrometry has been applied to the simultaneous determination of 16 nucleosides and nucleobases in medicinal extracts of various marine organisms.
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Cleaning up: Fabrics retain remnants of dry cleaning fluid
Date: Nov 1, 2011
Author: Steve Down
The dry cleaning fluid perchloroethylene is retained in fabrics for up to seven days after cleaning, presenting a potential health risk by inhalation and dermal absorption and warranting further studies on exposure of this potential carcinogen.
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Sweet tracer: Sucralose in drinking water is a marker for human activity
Date: Oct 15, 2011
Author: Steve Down
The majority of purified drinking water streams leaving domestic wastewater treatment plants in the US are contaminated with sucralose, suggesting that this artificial sweetener can be used as a marker for anthropogenic input in source and drinking water.
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Journal Highlight: Guidelines and recommended terms for expression of stable-isotope-ratio and gas-ratio measurement results
Date: Oct 9, 2011
Author:
To minimize confusion in the expression of measurement results of stable isotope and gas-ratio measurements, recommendations based on publications of the Commission on Isotopic Abundances and Atomic Weights of the International Union of Pure and Applied Chemistry (IUPAC) are presented.
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Tumour trials: Real-time boundary demarcation by ultrasonic aspiration and ambient mass spectrometry
Date: Oct 1, 2011
Author: Steve Down
Brain tissue can be analysed in real time in a surgical setting by a combination of ultrasonic aspiration and sonic spray mass spectrometry, raising the possibility of detecting tumour margins in the operating theatre without the addition of chemical tags. The procedure can easily be extended to other tissue types.
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Breath test boundaries: Food-borne interferents in test for invasive aspergillosis
Date: Sep 15, 2011
Author: Steve Down
Several foods and drinks are sources of 2-pentylfuran, a potential breath test marker for invasive aspergillosis, new research has shown. Patient diet should be taken into account to avoid false positive results if the GC/MS-based test is adopted.
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Journal Highlight: Synthesis, characterisation, and mass spectrometric detection of a pegylated EPO-mimetic peptide for sports drug testing purposes
Date: Sep 12, 2011
Author:
A pegylated EPO-mimetic peptide simulating the lead drug candidate peginesatide was synthesised as a model compound and characterised by gel electrophoresis, MALDI MS and LC/ESI-MS/MS after proteolytic digestion, to develop a method for detection in plasma.
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