Journal Highlight: Next-generation heteronuclear decoupling for high-field biomolecular NMR spectroscopy

Skip to Navigation

Ezine

  • Published: May 5, 2014
  • Author: spectroscopyNOW
  • Channels: NMR Knowledge Base
thumbnail image: Journal Highlight: Next-generation heteronuclear decoupling for high-field biomolecular NMR spectroscopy
<p>A novel low-power, broadband heteronuclear decoupling pulse is presented that generates minimal, ultra-low sidebands for ultra-high-field NMR spectroscopy.</p>

Next-generation heteronuclear decoupling for high-field biomolecular NMR spectroscopy

Angewandte Chemie International Edition, 2014, 53, 4475-4479
Franz Schilling, Lisa R. Warner, Naum I. Gershenzon, Thomas E. Skinner, Michael Sattler and Steffen J. Glaser

Abstract: Ultra-high-field NMR spectroscopy requires an increased bandwidth for heteronuclear decoupling, especially in biomolecular NMR applications. Composite pulse decoupling cannot provide sufficient bandwidth at practical power levels, and adiabatic pulse decoupling with sufficient bandwidth is compromised by sideband artifacts. A novel low-power, broadband heteronuclear decoupling pulse is presented that generates minimal, ultra-low sidebands. The pulse was derived using optimal control theory and represents a new generation of decoupling pulses free from the constraints of periodic and cyclic sequences. In comparison to currently available state-of-the-art methods this novel pulse provides greatly improved decoupling performance that satisfies the demands of high-field biomolecular NMR spectroscopy.

  • This paper is free to view for all users registered on spectroscopyNOW.com until the end of June 2014.
    After this time, you can purchase it using Pay-Per-View on Wiley Online Library.

Social Links

Share This Links

Bookmark and Share

Microsites

Suppliers Selection
Societies Selection

Banner Ad

Click here to see
all job opportunities

Copyright Information

Interested in separation science? Visit our sister site separationsNOW.com

Copyright © 2017 John Wiley & Sons, Inc. All Rights Reserved