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Automation in Proteomics and Genomics: An Engineering Case-Based Approach

Date: Mar 20, 2009

Author: Gil Alterovitz, Roseann Benson, Marco Ramoni

In the last decade DNA sequencing costs have decreased over a magnitude, largely because of increasing throughput by incremental advances in tools, technologies and process improvements. Further cost reductions in this and in related proteomics technologies are expected as a result of the development of new high-throughput techniques and the computational machinery needed to analyze data generated. Automation in Proteomics & Genomics: An Engineering Case-Based Approach describes the automation...

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Classics in Spectroscopy

Date: Mar 11, 2009

Author: Stefan Berger, Dieter Sicker

The first book of its kind to describe the art of NMR using everyday examples. This textbook will not only fascinate students wanting to learn about the topic, but also those experienced analytical chemists who are still inspired by their profession. The contents provide for easy reading by using natural products that everyone knows, such as caffeine, backed by an attractive layout with many pictures to visualize the topics. In addition, an in-depth analytical part makes the book a valuable teaching...

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Electron Paramagnetic Resonance: A Practitioners Toolkit

Date: Mar 6, 2009

Author: Marina Brustolon, Elio Giamello

This book offers a pragmatic guide to navigating through the complex maze of EPR/ESR spectroscopy fundamentals, techniques, and applications. Written for the scientist who is new to EPR spectroscopy, the editors have prepared a volume that de-mystifies the basic fundamentals without weighting readers down with detailed physics and mathematics, and then presents clear approaches in specific application areas. The first part presents basic fundamentals and advantages of electron paramagnetic resonance...

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Introduction to Proteomics

Date: Nov 7, 2008

Author: Agnieszka Kraj, Jerzy Silberring

Introduction to Proteomics is written by seasoned researchers with years of practical experience. In addition to comprehensive discussions of the basic concepts, techniques, and applications of the subject, the text also includes an extensive glossary and a chapter containing laboratory exercises and protocols. While mass spectrometry is central to proteomics, the book discusses all of the analytical techniques a student is likely to need when faced with real-world problems, such as sample preparation,...

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Fluorescence Methods and Applications: Spectroscopy, Imaging, and Probes

Date: Aug 8, 2008

Author: Otto S. Wolfbeis

This volume features papers on new spectroscopic methods and techniques, the development and application of fluorescent probes, and new techniques and applications of fluorescence imaging. Specific areas include the following: fluorescence lifetime, fluorescence (in vivo) imaging, time-resolved fluorescence, luminescence anisotropy, fluorescent (NMIR) labels, luminescent lanthanides, fluorescent sensors and probes, fluorescence microscopy, FRET, fluorescent nanoparticles and dots, high-throughput...

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Even Electron Mass Spectrometry with Biomolecule Applications

Date: May 20, 2008

Author: Bryan M. Ham

In addition to the essential theoretical background and fundamental principles, this unique reference presents a detailed, step-by-step methodology for interpreting even electron mass spectrometry results. Specific chapters are devoted to: proteomics; biomolecule spectral interpretation of small molecules; biomolecule spectral interpretation of biological macromolecules; and MALDI-TOF-Postsource Decay (PSD). Chapters feature detailed examples, questions, and problems to help readers solidify their...

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Preclinical Development Handbook: ADME and Biopharmaceutical Properties

Date: Apr 29, 2008

Author: Shayne Cox Gad

A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for...

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Trace Quantitative Analysis by Mass Spectrometry

Date: Apr 18, 2008

Author: Robert K. Boyd, Cecilia Basic, Robert A. Bethem

This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding...

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Practical Gamma-ray Spectroscopy, 2nd Edition

Date: Apr 18, 2008

Author: Gordon Gilmore

The Second Edition of Practical Gamma-Ray Spectrometry has been completely revised and updated, providing comprehensive coverage of the whole gamma-ray detection and spectrum analysis processes. Drawn on many years of teaching experience to produce this uniquely practical volume, issues discussed include the origin of gamma-rays and the issue of quality assurance in gamma-ray spectrometry. This new edition also covers the analysis of decommissioned nuclear plants, computer modelling systems for...

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Microsystem Engineering of Lab-on-a-Chip Devices

Date: Apr 16, 2008

Author: Oliver Geschke, Henning Klank, Pieter Telleman

Edited by an interdisciplinary team of scientists at one of the leading centers for microsystem research, this second edition retains the proven structure of its predecessor, enlarged by around 10%. Focusing on analytical applications mainly in life sciences, this is an invaluable companion for fast and automated analytical procedures, providing a concise practical approach to microtechnology.

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