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Bactericidal polymers: Phosphorus NMR links up activity

Date: Sep 15, 2018

Author: David Bradley

Researchers in Canada have used phosphorus-31 nuclear magnetic resonance (NMR) spectroscopy to study hydrophilic phosphonium polymers that have surprising antibacterial activity and selectivity.

Read More thumbnail image: Bactericidal polymers Phosphorus NMR links up activity

Journal Highlight: Important issues in plant tissues analyses by HR‐MAS NMR

Date: Sep 3, 2018

Author: spectroscopyNOW

A study of the method variables in the HR‐MAS NMR analysis of plant tissues has highlighted the need for standardised sample preparation and instrumental setup protocols in order to achieve high reproducibility and reliable data.

Read More thumbnail image: Journal Highlight Important issues in plant tissues analyses by HRMAS NMR

Autophagy: NMR and MS reveal tumour regrowth mechanism

Date: Sep 1, 2018

Author: David Bradley

The combined forces of nuclear magnetic resonance (NMR) spectroscopy and mass spectrometry have been used in research that shows how cell metabolism affects the ability of cells to undergo a survival program called autophagy during cancer chemotherapy allowing a tumour to regrow.

Read More thumbnail image: Autophagy NMR and MS reveal tumour regrowth mechanism

Elastic air: NMR of hydrogels

Date: Aug 15, 2018

Author: David Bradley

Superflexible aerogels can be used as highly efficient absorbents, thermal insulators, and pressure sensors. Now, a team from Japan with a little help from nuclear magnetic resonance (NMR) spectroscopy have developed super-elastic aerogels that can be processed easily and at low cost.

Read More thumbnail image: Elastic air NMR of hydrogels

Fungal killer: NMR reveals wall architecture

Date: Aug 1, 2018

Author: David Bradley

There are very few effective antifungal agents in the pharmaceutical arsenal and unfortunately, many types of fungal infection can kill. New research based on solid-state nuclear magnetic resonance (NMR) spectroscopy has looked at fungal cell wall and revealed details of its architecture that might be a new target for drugs to combat such infections.

Read More thumbnail image: Fungal killer NMR reveals wall architecture

Journal Highlight: Seafood phospholipids: Extraction efficiency and phosphorous nuclear magnetic resonance spectroscopy (31P NMR) profiles

Date: Jul 30, 2018

Author: spectroscopyNOW

The absolute concentration of phospholipids in five marine tissues has been determined using quantitative phosphorous nuclear magnetic resonance spectroscopy.

Read More thumbnail image: Journal Highlight Seafood phospholipids Extraction efficiency and phosphorous nuclear magnetic resonance spectroscopy 31P NMR profiles

Packaged paclitaxel: NMR unravels cyclodextrin

Date: Jul 15, 2018

Author: David Bradley

Supramolecular nanoassemblies that can emulate and perhaps modulate biological processes have become a focus of research. Nuclear magnetic resonance (NMR) spectroscopy and other techniques have now been used to follow one such self-assembled system, a cyclodextrin molecule bearing a photoisomer and hooked to cellular microtubules using the anticancer agent paclitaxel.

Read More thumbnail image: Packaged paclitaxel NMR unravels cyclodextrin

Journal Highlight: Insight into old and new pure shift nuclear magnetic resonance methods for enantiodiscrimination

Date: Jul 2, 2018

Author: spectroscopyNOW

Recent developments in the pure shift 1H NMR-based methods for enantiomer resolution and enantiodiscrimination have been reviewed and various pure shift methods used for enantiodiscrimination and measurement of enantiomeric excess discussed.

Read More thumbnail image: Journal Highlight Insight into old and new pure shift nuclear magnetic resonance methods for enantiodiscrimination

Motor neurone link: NMR investigates proteins

Date: Jul 1, 2018

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy technology has been used to investigate how two proteins important in a hereditary form of motor neurone disease, Kap-β2 importin and the FUS protein, bind to each other. The research could ultimately lead the way to a better understanding of this neurodegenerative disease.

Read More thumbnail image: Motor neurone link NMR investigates proteins

Bronze Age olive oil: NMR in old Italy

Date: Jun 15, 2018

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GC-MS), and other techniques has been used to analyse an ancient pottery. The data suggest that "Italians" were using olive oil at least 700 hundred years earlier than previously thought, in the early Bronze Age.

Read More thumbnail image: Bronze Age olive oil NMR in old Italy
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