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Packaged paclitaxel: NMR unravels cyclodextrin

Date: Jul 15, 2018

Author: David Bradley

Supramolecular nanoassemblies that can emulate and perhaps modulate biological processes have become a focus of research. Nuclear magnetic resonance (NMR) spectroscopy and other techniques have now been used to follow one such self-assembled system, a cyclodextrin molecule bearing a photoisomer and hooked to cellular microtubules using the anticancer agent paclitaxel.

Read More thumbnail image: Packaged paclitaxel NMR unravels cyclodextrin

Journal Highlight: Insight into old and new pure shift nuclear magnetic resonance methods for enantiodiscrimination

Date: Jul 2, 2018

Author: spectroscopyNOW

Recent developments in the pure shift 1H NMR-based methods for enantiomer resolution and enantiodiscrimination have been reviewed and various pure shift methods used for enantiodiscrimination and measurement of enantiomeric excess discussed.

Read More thumbnail image: Journal Highlight Insight into old and new pure shift nuclear magnetic resonance methods for enantiodiscrimination

Motor neurone link: NMR investigates proteins

Date: Jul 1, 2018

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy technology has been used to investigate how two proteins important in a hereditary form of motor neurone disease, Kap-β2 importin and the FUS protein, bind to each other. The research could ultimately lead the way to a better understanding of this neurodegenerative disease.

Read More thumbnail image: Motor neurone link NMR investigates proteins

Bronze Age olive oil: NMR in old Italy

Date: Jun 15, 2018

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy, gas chromatography-mass spectrometry (GC-MS), and other techniques has been used to analyse an ancient pottery. The data suggest that "Italians" were using olive oil at least 700 hundred years earlier than previously thought, in the early Bronze Age.

Read More thumbnail image: Bronze Age olive oil NMR in old Italy

Journal Highlight: Nuclear magnetic resonance (NMR)‐based metabolomics for cancer research

Date: Jun 4, 2018

Author: spectroscopyNOW

This review provides a snapshot of the trending NMR techniques and the statistical analysis involved in the metabolomics of diseases, with emphasis on advances in NMR methodology developed for cancer research.

Read More thumbnail image: Journal Highlight Nuclear magnetic resonance NMRbased metabolomics for cancer research

Diamonds are for NMR: Cutting costs

Date: Jun 1, 2018

Author: David Bradley

 Diamonds are relatively inexpensive when compared to making and sustaining superconducting magnets. As such, new research offers the possibility of a very-low-cost alternative to multimillion-dollar magnetic resonance imaging (MRI) equipment and the costly nuclear magnetic resonance spectrometers used in drug discovery and other areas by using the former to preclude the need for the latter.

Read More thumbnail image: Diamonds are for NMR Cutting costs

Time team: NMR finds crystal

Date: May 15, 2018

Author:

Nuclear magnetic resonance (NMR) spectroscopy has been involved in uncovering hints of a time crystal, a form of matter that "ticks" when exposed to an electromagnetic pulse. The time crystal was found in the most unlikely of places: a crystal garden kit.

Read More thumbnail image: Time team NMR finds crystal

Counting tree rings: NMR helps in climate calculations

Date: May 1, 2018

Author: David Bradley

Using a decade-long sequence of annual growth rings from pine trees, scientists have then incorporated data from nuclear magnetic resonance (NMR) spectroscopy into a study to help them correlate carbon metabolism with climate change.

Read More thumbnail image: Counting tree rings NMR helps in climate calculations

Journal Highlight: NMReDATA, a standard to report the NMR assignment and parameters of organic compounds

Date: Apr 30, 2018

Author: spectroscopyNOW

A new format called NMReDATA (for nuclear magnetic resonance extracted data) has been proposed for associating the NMR parameters extracted from 1D and 2D spectra of organic compounds to the proposed chemical structures.

Read More thumbnail image: Journal Highlight NMReDATA a standard to report the NMR assignment and parameters of organic compounds

Prostate cancer: NMR determines aggressiveness

Date: Apr 15, 2018

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy could help solve a commonly intractable medical problem: how to determine the aggressiveness of prostate cancer. The new approach could help oncologists identify which tumours could be life threatening and need radical treatment

Read More thumbnail image: Prostate cancer NMR determines aggressiveness
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