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Magnetic benchmark: Record-breaking thin film

Date: Feb 15, 2018

Author: David Bradley

US researchers have developed a new magnetic thin film that could finally break through the Slater-Pauling limit on magnetic density in a material. With this decades-old benchmark circumvented new applications and devices might be possible.

Read More thumbnail image: Magnetic benchmark Record-breaking thin film

Amyotrophic lateral sclerosis: NMR spots atomic changes

Date: Feb 1, 2018

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy has been used to reveal for the first time the atom-by-atom changes that take place in a family of proteins associated with amyotrophic lateral sclerosis (ALS). This group of lethal brain disorders leads to frontotemporal dementia and degenerative diseases of muscle and bone.

Read More thumbnail image: Amyotrophic lateral sclerosis NMR spots atomic changes

Journal Highlight: A review of NMR methods used in the study of the structure and dynamics of ionic liquids

Date: Jan 29, 2018

Author: spectroscopyNOW

This mini-review presents a brief research summary of the applications of NMR spectroscopy to the structure and dynamics of pure ionic liquids and their mixtures with lithium salts.

Read More thumbnail image: Journal Highlight A review of NMR methods used in the study of the structure and dynamics of ionic liquids

The dawn of life: NMR has (some of) the details

Date: Jan 15, 2018

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy and other techniques have been used to study the linked cycles of oxidative decarboxylation of glyoxylate. Such cycles could be perceived as being proto-metabolic analogues of the citric acid cycle on which life depends and might provide a new clue as to how life on earth emerged from the primordial soup.

Read More thumbnail image: The dawn of life NMR has some of the details

Protein dynamics: NMR focuses on GPCRs

Date: Jan 5, 2018

Author: David Bradley

Nuclear magnetic resonance (NMR) spectroscopy has allowed US researchers to peer into the heart of a key protein used in drug design to reveal dynamic structural features that may lead to new ways for targeting disease.

Read More thumbnail image: Protein dynamics NMR focuses on GPCRs

Journal Highlight: Nuclear magnetic relaxation dispersion of murine tissue for development of T1 (R1) dispersion contrast imaging

Date: Jan 1, 2018

Author: spectroscopyNOW

The spin–lattice relaxation rate (R1) dispersion of murine tissues from 0.24 mT to 3 T has been assessed using a combination of ex vivo and in vivo spin–lattice relaxation rate measurements on murine tissue.

Read More thumbnail image: Journal Highlight Nuclear magnetic relaxation dispersion of murine tissue for development of T1 R1 dispersion contrast imaging

One flu over: NMR insights

Date: Dec 15, 2017

Author: David Bradley

When you catch influenza, the virus hijacks the inner workings of your cells to make copies of itself. The copies accumulate in viral buds that then break free from the host cell to infect another host. Researchers at Massachusetts Institute of Technology have now used solid-state nuclear magnetic resonance (NMR) spectroscopy to obtain a clear picture of how these buds pinch off from the host cell membrane.

Read More thumbnail image: One flu over NMR insights

Fluorine pharma: Quality control by NMR

Date: Dec 1, 2017

Author: David Bradley

Routine analysis and quality control of fluorine-containing pharmaceuticals could now be possible with the application of the relatively simple and straightforward technique of fluorine-19 nuclear magnetic resonance (NMR) spectroscopy, according to researchers in Kenya and Germany.

Read More thumbnail image: Fluorine pharma Quality control by NMR

Journal Highlight: 31P NMR of the pyruvate kinase reaction: An undergraduate experiment in enzyme kinetics

Date: Nov 27, 2017

Author: spectroscopyNOW

A simple 31P NMR tube experiment has been developed that allows students to examine the enzyme kinetics and equilibrium constant of the reaction catalyzed by pyruvate kinase.

Read More thumbnail image: Journal Highlight 31P NMR of the pyruvate kinase reaction An undergraduate experiment in enzyme kinetics

Pick up a prion: Solid state NMR spots the differences

Date: Nov 15, 2017

Author: David Bradley

Researchers in the USA have used solid-state nuclear magnetic resonance (NMR) spectroscopy to study the rogue proteins involved in familial human cerebral amyloid angiopathy (CAA). This hereditary neurodegenerative condition is one of the family of prion diseases that afflict mammals and include bovine spongiform encephalopathy (often referred to colloquially as "mad cow disease"), Creutzfeldt-Jakob disease in humans, their equivalents in cats, mice, hamsters and other animals.

Read More thumbnail image: Pick up a prion Solid state NMR spots the differences
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