NMR Knowledge Base / Ezine
The spicy disciplinarian
Date: Mar 15, 2009
Author: David Bradley
Solid state NMR has been used to explain why curcumin, one of the phyisiologically active components of the yellow spice turmeric has wound healing and other medicinal properties.
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Automatic phase correction of 2D NMR spectra by a whitening method
Date: Mar 6, 2009
Author:
A new method for the automatic phase correction of multidimensional NMR spectra is described. It is based on the whitening concept formulated as the 'maximization of the number of white pixels into a bitmap that corresponds to the spectrum'.
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Plug and play molecular logic
Date: Mar 1, 2009
Author: David Bradley
A "plug and play" approach to building molecular logic units has been developed by chemists in the UK and Thailand. The team used various spectroscopic techniques, including fluorescence and NMR to monitor their logical constructions.
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Farming phosphorus
Date: Feb 15, 2009
Author: David Bradley
Phosphorus NMR can help distinguish between the nature of organic and non-organic farming and provide clues about how phosphorus from both sources affects waterways and coasts.
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Getting inside bacteria with NMR
Date: Feb 1, 2009
Author: David Bradley
Solid-state nuclear magnetic resonance spectroscopy has been used for the first time to investigate large membrane proteins in bacteria, allowing researchers to investigate exactly how the sensory organs of these single-celled organisms function.
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Bilious NMR
Date: Jan 15, 2009
Author: David Bradley
High-field NMR spectroscopy has been used for the first time to analyse human liver bile, as opposed to gall bladder bile, with a view to improving liver transplant success.
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Electronic structure and biological activity of chosen DDT-type insecticides studied by 35Cl-NQR
Date: Jan 9, 2009
Author:
A correlation between the electronic structure and biological activity of chosen DDT-type insecticides has been analyzed on the basis of the 35Cl-NQR spectroscopy. The 35Cl-NQR resonance frequencies measured at 77K have been correlated with the LD50 parameter that characterizes the biological activity of these insecticides.
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Folding issues
Date: Jan 1, 2009
Author: David Bradley
NMR spectroscopy is helping US chemists work out shorter and simpler routes to protein-based drugs for treating a wide range of illnesses including diabetes, cancer, and hepatitis.
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Untangling Alzheimer molecules
Date: Dec 15, 2008
Author: David Bradley
NMR provides new clues about how a dipeptide molecule blocks the formation of the toxic amyloid beta-peptide aggregates in the mouse brain. The discovery could put paid to the theory that amyloid beta-peptide causes Alzheimer's disease and suggest a therapeutic lead that focus on the real culprit at an earlier stage.
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Organic soil matters
Date: Dec 1, 2008
Author: David Bradley
Could the earth beneath our feet hold the key to climate change? According to scientists at the University of Toronto Scarborough their NMR results show that global warming is changing the molecular structure of organic matter in soil.
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