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Cagey about water: NMR in a fullerene

Date: Jul 1, 2014

Author: David Bradley

The all-carbon, soccerball-shaped fullerene, C60, molecule provides the most compact of cryoscopic NMR tubes for studying the behaviour of water, according to researchers at the Universities of Nottingham and Southampton, in UK and Columbia University in New York, USA.

Read More thumbnail image: Cagey about water NMR in a fullerene

Journal Highlight: 1H NMR based metabolic profiling in Crohn's disease by random forest methodology

Date: Jun 30, 2014

Author: spectroscopyNOW

1H NMR spectroscopy of the serum metabolites of patients with Crohn's disease, supported by random forest methodology, showed that valine and isoleucine are differentiating metabolites for diagnosis.

Read More thumbnail image: Journal Highlight 1H NMR based metabolic profiling in Crohns disease by random forest methodology

PSYCHE NMR: High-resolution not all in the mind

Date: Jun 15, 2014

Author: David Bradley

Researchers at the University of Manchester, UK, and their colleagues, have developed an ultra-high-resolution NMR spectroscopy technique, which they have given the wonderful acronym PSYCHE, for pure shift yielded by chirp excitation.

Read More thumbnail image: PSYCHE NMR High-resolution not all in the mind

Journal Highlight: Quantitative 2D liquid-state NMR

Date: Jun 2, 2014

Author: spectroscopyNOW

This review aims at presenting recent efforts to reach a high trueness and precision in quantitative measurements of liquids by 2D NMR.

Read More thumbnail image: Journal Highlight Quantitative 2D liquid-state NMR

Xenon boost: Medical microfluidics

Date: Jun 1, 2014

Author:

A microfluidic device that can generate polarised xenon-129 gas and detect it by nuclear magnetic resonance, NMR, spectroscopy at tiny concentrations has been developed by an international team. The device could give a noble boost to biomedical analysis and medical imaging.

Read More thumbnail image: Xenon boost Medical microfluidics

Saucy solution: HIV antivirals

Date: May 15, 2014

Author: David Bradley

US researchers are using nuclear magnetic resonance spectroscopy to help inform their virology efforts in the hope of develop new, potent antiviral agents for the treatment of HIV, human immunodeficiency virus.

Read More thumbnail image: Saucy solution HIV antivirals

Journal Highlight: Next-generation heteronuclear decoupling for high-field biomolecular NMR spectroscopy

Date: May 5, 2014

Author: spectroscopyNOW

A novel low-power, broadband heteronuclear decoupling pulse is presented that generates minimal, ultra-low sidebands for ultra-high-field NMR spectroscopy.

Read More thumbnail image: Journal Highlight Next-generation heteronuclear decoupling for high-field biomolecular NMR spectroscopy

Human herpes virus 4: No bar to understanding

Date: May 1, 2014

Author: David Bradley

NMR spectroscopy has been used to investigate how a viral protein in human herpes virus 4 (also known as Epstein-Barr) regulates the activity of a second essential protein and so reveals a possible new target for the development of antiviral drugs against this common infectious agent.

Read More thumbnail image: Human herpes virus 4 No bar to understanding

Inflammatory spectroscopy: Hearty biomarkers

Date: Apr 15, 2014

Author: David Bradley

A research team in the USA has discovered that elevated levels, as identified by nuclear magnetic resonance spectroscopy, of two recently identified proteins in the body can act as markers for inflammation and thus indicators of the presence of cardiovascular disease.

Read More thumbnail image: Inflammatory spectroscopy Hearty biomarkers

Predicting pre-eclampsia: NMR metabolomics

Date: Apr 1, 2014

Author: David Bradley

Researchers in Norway have found a useful set of biomarkers in urine and serum samples using NMR spectroscopy that are different between women who are not pregnant, those with normal pregnancies, and those with the debilitating and potentially life-threatening condition of pre-eclampsia.

Read More thumbnail image: Predicting pre-eclampsia NMR metabolomics
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