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Terrestrial NMR: Extra

Date: Sep 1, 2014

Author: David Bradley

The Earth's magnetic field is strong enough for experiments in low-field NMR spectroscopy according to a research team from Lawrence Berkeley National Laboratory, which is developing the technique for analysis of fluids in situ in their native environments.

Read More thumbnail image: Terrestrial NMR Extra

Chemical rewiring: Nerve growth

Date: Aug 15, 2014

Author: David Bradley

New research from and international team using NMR spectroscopy suggests that a single, small molecule might be able to persuade nerves damaged by injury to grow new connections, offering a future hope for people who suffer spinal injuries and paralysis.

Read More thumbnail image: Chemical rewiring Nerve growth

Journal Highlight: Color-discriminating retinal configurations of sensory rhodopsin I by photo-irradiation solid-state NMR spectroscopy

Date: Aug 4, 2014

Author: spectroscopyNOW

The photoreactions of sensory rhodopsin I were monitored with the 13C NMR signals of [20-13C]retnal-SrSRI using in situ photo-irradiation solid-state NMR spectroscopy.

Read More thumbnail image: Journal Highlight Color-discriminating retinal configurations of sensory rhodopsinI by photo-irradiation solid-state NMR spectroscopy

Autoimmune mechanism: NMR and X-ray clues

Date: Aug 1, 2014

Author: David Bradley

NMR spectroscopists, X-ray crystallographers and their colleagues have taken an important step closer to understanding the molecular mechanism behind autoimmune diseases. They have solved the three-dimensional structure of the Roquin protein when it is bound to messenger RNA. The results revealed that there is a much wider range of functionally important Roquin binding partners than previously assumed.

Read More thumbnail image: Autoimmune mechanism NMR and X-ray clues

Multitasking protein: Nucleophosmin 1

Date: Jul 15, 2014

Author: David Bradley

Nuclear magnetic resonance spectroscopy has been used to demonstrate how one segment of an important regulatory protein, nucleophosmin 1 (NPM1), helps it to fulfil several roles, including tumour suppression, according to researchers at St Jude Children's Research Hospital, Memphis, Tennessee and the Medical Research Council Laboratory of Molecular Biology, in Cambridge, UK. The findings could have implications for the development of novel anticancer drugs.

Read More thumbnail image: Multitasking protein Nucleophosmin 1

Cagey about water: NMR in a fullerene

Date: Jul 1, 2014

Author: David Bradley

The all-carbon, soccerball-shaped fullerene, C60, molecule provides the most compact of cryoscopic NMR tubes for studying the behaviour of water, according to researchers at the Universities of Nottingham and Southampton, in UK and Columbia University in New York, USA.

Read More thumbnail image: Cagey about water NMR in a fullerene

Journal Highlight: 1H NMR based metabolic profiling in Crohn's disease by random forest methodology

Date: Jun 30, 2014

Author: spectroscopyNOW

1H NMR spectroscopy of the serum metabolites of patients with Crohn's disease, supported by random forest methodology, showed that valine and isoleucine are differentiating metabolites for diagnosis.

Read More thumbnail image: Journal Highlight 1H NMR based metabolic profiling in Crohns disease by random forest methodology

PSYCHE NMR: High-resolution not all in the mind

Date: Jun 15, 2014

Author: David Bradley

Researchers at the University of Manchester, UK, and their colleagues, have developed an ultra-high-resolution NMR spectroscopy technique, which they have given the wonderful acronym PSYCHE, for pure shift yielded by chirp excitation.

Read More thumbnail image: PSYCHE NMR High-resolution not all in the mind

Journal Highlight: Quantitative 2D liquid-state NMR

Date: Jun 2, 2014

Author: spectroscopyNOW

This review aims at presenting recent efforts to reach a high trueness and precision in quantitative measurements of liquids by 2D NMR.

Read More thumbnail image: Journal Highlight Quantitative 2D liquid-state NMR

Xenon boost: Medical microfluidics

Date: Jun 1, 2014

Author:

A microfluidic device that can generate polarised xenon-129 gas and detect it by nuclear magnetic resonance, NMR, spectroscopy at tiny concentrations has been developed by an international team. The device could give a noble boost to biomedical analysis and medical imaging.

Read More thumbnail image: Xenon boost Medical microfluidics
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