NMR Knowledge Base / Ezine
In its element: Fluorine
Date: Jul 15, 2012
Author: David Bradley
Fluorine-19 NMR spectroscopy has been used to reveal how despite its renowned reactivity, elemental fluorine can exist in nature.
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Journal Highlight: Use of NMR in fish processing optimization: a review of recent progress
Date: Jul 2, 2012
Author: spectroscopyNOW
An overview of general trends in the application of NMR related to fish processing and quality is presented with some viewpoints on the current situation.
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New job for old drug: Cisplatin in ALS
Date: Jul 1, 2012
Author: David Bradley
The well-known and well-used anticancer drug cisplatin looks set to be the starting point for the development of new treatments for the incurable disorder motor neuron disease.
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Carbon capture: Solar-powered option
Date: Jun 15, 2012
Author: David Bradley
A US team has suggested a novel reaction mechanism that can mimic photosynthesis in the binding of carbon dioxide using light energy captured by silicon nanowires.
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Journal Highlight: 1H-NMR Simultaneous identification of health-relevant compounds in propolis extracts
Date: Jun 4, 2012
Author: spectroscopyNOW
The use of 1H-NMR for the simultaneous recognition of phenolic compounds in complex matrices, such as propolis extracts, has been demonstrated using appropriate tools for spectra pre-treatment and analysis.
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NMR gets the needle: Bacterial target pinpointed
Date: Jun 1, 2012
Author: David Bradley
The structure of a "needle" used by various bacteria, among them strains that cause bubonic plague, enterohaemorrhagic colitis, typhoid fever, Shigella dysentery and cholera, to get into host cells has been obtained at atomic resolution using NMR and other techniques. The research could ultimately lead to the development of novel drug to combat these and other diseases.
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Journal Highlight: Benchmark calculations of 29Si–1H spin–spin coupling constants across double bond
Date: May 15, 2012
Author: spectroscopyNOW
Benchmark calculations of geminal and vicinal 29Si–1H spin–spin coupling constants across double bond in three reference alkenylsilanes have been carried out at both DFT and SOPPA levels in comparison with experiment.
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Walk on by: The light at the end of the track
Date: May 15, 2012
Author: David Bradley
British researchers have created a molecular track to emulate this process and added a small molecule that can shuffle back and forth like a courier on the track.
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Nerve block: Halting pain at a snail's pace
Date: Apr 30, 2012
Author: David Bradley
Conotoxins from the predatory cone snail work even at very low levels to block nerve signals. A new NMR spectroscopic study has investigated the structures of a specific conotoxin with a view to developing these compounds, or their derivatives, as novel painkillers.
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Journal Highlight: Sucrose in aqueous solution revisited, Part 2: Adaptively biased molecular dynamics simulations and computational analysis of NMR relaxation
Date: Apr 2, 2012
Author:
Molecular dynamics simulations of sucrose in water at various temperatures track closely with experimental results, and are consistent with a model in which sucrose conformational fluctuations are limited.
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