NMR Knowledge Base / Ezine
Playing protein tag: Repeatable NMR
Date: Oct 1, 2012
Author: David Bradley
Chemists at the University of California San Diego have developed a method that allows them, for the first time, to attach chemical probes on to proteins and remove them again in a straightforward and repeatable cycle. The method will facilitate NMR spectroscopy for metabolic and other research studies.
Read More
MOFs: NMR reveals inner secrets
Date: Sep 15, 2012
Author: David Bradley
A large international research team from Canada and China has shown for the first time that zinc-67 solid-state NMR spectroscopy could be as useful in analysing the zinc atom centres in a new type of synthetic porous materials known as metal-organic frameworks (MOFs) as its aluminium-based counterpart, aluminium-27 NMR is in studying the more widely known natural porous zeolite minerals.
Read More
Journal Highlight: Applications of NMR metabolomics to the study of foodstuffs: Truffle, kiwifruit, lettuce, and sea bass
Date: Sep 3, 2012
Author: spectroscopyNOW
The use of NMR to study the metabolomes of foodstuffs of different origin (truffle, kiwifruit, lettuce, sea bass) with different metabolite compositions, processing, and storage procedures, is reviewed.
Read More
Move like caged hydrogen: Buckyball traps
Date: Sep 1, 2012
Author: David Bradley
Cryogenic NMR spectroscopy and other techniques has been used to investigate how small molecules, including water, are trapped by the all-carbon cages known as fullerenes. The work might open up the possibility of using such caged systems as alternative contrast agents for magnetic resonance imaging.
Read More
Supercritical carbon dioxide: Forming formic acid
Date: Aug 15, 2012
Author: David Bradley
Carbon dioxide can be both starting material for the production of formic acid through hydrogenation and also the solvent for the reaction if held in the supercritical; the usual complexities of extraction of product from solvent essentially removed as the solvent can be evaporated by simply releasing the pressure from the system and trapping the carbon dioxide gas released. NMR spectroscopy allows the German inventors of the process to keep track of reactants and products.
Read More
Journal Highlight: Comparison of the metabolic profiling of hepatitis B virus-infected cirrhosis and alcoholic cirrhosis patients by using 1H NMR-based metabonomics
Date: Aug 6, 2012
Author: spectroscopyNOW
Proton NMR was used to reveal the serum metabolic characteristics of hepatitis B virus-infected cirrhosis and alcoholic cirrhosis patients and to find the specific serum biomarkers associated with the diseases.
Read More
Stellar effort: New chemical bond revealed
Date: Aug 1, 2012
Author: David Bradley
Quantum mechanics calculations suggest that the intense magnetic field around a type of fast-spinning, high-density star known as a white dwarf might be strong enough to distil a new type of chemistry.
Read More
In its element: Fluorine
Date: Jul 15, 2012
Author: David Bradley
Fluorine-19 NMR spectroscopy has been used to reveal how despite its renowned reactivity, elemental fluorine can exist in nature.
Read More
Journal Highlight: Use of NMR in fish processing optimization: a review of recent progress
Date: Jul 2, 2012
Author: spectroscopyNOW
An overview of general trends in the application of NMR related to fish processing and quality is presented with some viewpoints on the current situation.
Read More
New job for old drug: Cisplatin in ALS
Date: Jul 1, 2012
Author: David Bradley
The well-known and well-used anticancer drug cisplatin looks set to be the starting point for the development of new treatments for the incurable disorder motor neuron disease.
Read More
