The application of spectroscopy in proteomics
Techniques include LC-MS, LC-MS/MS, GC-MS, MALDI-TOF-MS and metabolomics.
In recent years, life sciences have shifted towards a more holistic approach to the study of organisms, considering them as a whole rather than as a sum of individual parts. This approach, known as systems biology, is necessarily interdisciplinary, requiring the use of physiological, physical, molecular, biochemical and chemical methods to observe and measure the response of an organism to diverse conditions. The omics technologies, such as genomics, transcriptomics, proteomics and metabolomics, are...Read More
Automated methods for charge heterogeneity detection such as imaged capillary isoelectric focusing (icIEF) have been widely adopted by the biopharma industry. These techniques provide rapid high resolution charge variant separation with easy method development and minimal start up time. This webinar will provide an overview of the iCE technology and its applications.Read More
Two seconds here could save you months in the lab by using Wiley's Compound Search tool. Check the database coverage now... it's free! We understand that you don't have time to wade through thousands of results. Compound Search's sole purpose is to tell you whether a compound appears in a specific database so that you'll know whether that database meets your needs. To speed this up, we provide exact structure matches only. Compound Search enables users to perform...Read More
Jul 21, 2014
This review aims to summarize and analyze the different proteomic approaches used to study granzymes and discusses both the convincing and controversial outcomes.
Jul 20, 2014
Natural insulin and its synthetic variants present in the human body can be distinguished by mass spectrometry following global immunoaffinity extraction, a technique that will be useful in clinical, forensic and sports doping settings.
Jul 3, 2014
The canine urinary proteome has been characterised in the US and compared to that of human urine, to see if it can act as a model for the study of human diseases.View All Ezines
May 22, 2010
This article on the history and impact of mass spectrometry in the pharmaceutical industry is the first in a new series for Pharmaceutical Formulation & Quality, the premier source of news and information for pharmaceutical and biopharmaceutical industry professionals.
Sep 28, 2005
A glossary of common terms in proteomics, reproduced with the permission of Cambridge Healthtech Institute
Sep 28, 2005
This special feature paper, published in the Journal of Mass Spectrometry, highlights the benefits of using LC/MS/MS methods in proteome analysis in favour of the traditional 2DE/MS technique.View All Education Articles
Timothy D. Veenstra
Jul 19, 2013
May 1, 2013
Walter A. Korfmacher
Mar 12, 2013
Jul 23, 2014
Jul 13, 2014
Jul 24, 2014
Waters has acquired the rapid evaporative ionization mass spectrometry technology behind the 'intelligent knife', a device for real-time diagnostics during surgery.
Date: Jul 15, 2014
Fraser McLeod, Vice President & General Manager for HPLC at Thermo Fisher Scientific talks exclusively to separationsNOW.com about the game-changing Vanquish UHPLC system.