Skyline software for Bruker proteomics TOF instruments

A new version of the Skyline proteomics software has been produced by the MacCoss Lab Team at the University of Washington School of Medicine for the Bruker maXis™ series of electrospray-Qq-TOF mass spectrometers. The news was announced at the 11th HUPO Annual World Congress in Boston, MA.

Skyline is a Windows-based application for building quantitative methods based on selected reaction monitoring (SRM), multiple reaction monitoring (MRM) and full-scan MS and MS/MS and analyzing the subsequent data. Following its integration with many other instrument platforms, its full capabilities are being extended to the Bruker ESI-Qq-TOF range this autumn.

In a recent development Skyline also announced that its users will be able to directly access the raw mass spectrometry data points, including m/z ratios, times, and intensities from data files generated by various instrument manufacturers. Importing data from different MS vendors will improve the ability of researchers to share methodology and data across instrument platforms.