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Genotoxic Impurities: Strategies for Identification and Control

Date: Feb 15, 2011

Author: Andrew Teasdale

This book examines genotoxic impurities and their impact on the pharmaceutical industry. Specific sections examine this from both a toxicological and analytical perspective. Within these sections, the book defines appropriate strategies to both assess and ultimately control genotoxic impurities, thus aiding the reader to develop effective control measures. An opening section covers the development of guidelines and the threshold of toxicological concern (TTC) and is followed by a section on...

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Handbook of Alcoholic Beverages: Technical, Analytical and Nutritional Aspects, 2 Volume Set

Date: Jan 28, 2011

Author: Alan J. Buglass

A comprehensive two- volume set that describes the science and technology involved in the production and analysis of alcoholic beverages. At the heart of all alcoholic beverages is the process of fermentation, particularly alcoholic fermentation, whereby sugars are converted to ethanol and many other minor products. The Handbook of Alcoholic Beverages tracks the major fermentation process, and the major chemical, physical and technical processes that accompany the production of the world’s most...

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Analytical Methods for Therapeutic Drug Monitoring and Toxicology

Date: Jan 28, 2011

Author: Q. Alan Xu, Timothy L. Madden

This book is a compilation of summarized analytical methods designed to serve the needs of pharmacologists, toxicologists, and other allied health professionals involved the development, use, or monitoring of pharmaceuticals. The summaries are structured monographs on 511 different drug entities detailing 964 different analytical methods, providing the reader with a thorough description of method validation. These analytical methods include not only high performance liquid chromatography (HPLC), but also...

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Handbook of Fluorescence Spectroscopy and Imaging: From Ensemble to Single Molecules

Date: Jan 26, 2011

Author: Markus Sauer, Johan Hofkens, Jörg Enderlein

Providing much-needed information on fluorescence spectroscopy and microscopy, this ready reference covers detection techniques, data registration, and the use of spectroscopic tools, as well as new techniques for improving the resolution of optical microscopy below the resolution gap. Starting with the basic principles, the book goes on to treat fluorophores and labeling, single-molecule fluorescence spectroscopy and enzymatics, as well as excited state energy transfer, and super-resolution fluorescence...

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Regulated Bioanalytical Laboratories: Technical and Regulatory Aspects from Global Perspectives

Date: Jan 21, 2011

Author: Michael Zhou

This book provides useful information for bioanalytical / analytical scientists, analysts, quality assurance managers, and all personnel in bioanalytical laboratories through all aspects of bioanalytical technical and regulatory perspectives within bioanalytical operations and processes. Readers learn how to develop and implement strategies for routine, non-routine, and standard bioanalytical methods and on the entire equipment hardware and software qualification process. The book also gives guidelines on...

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Raman Spectroscopy in Graphene Related Systems

Date: Jan 14, 2011

Author: Ado Jorio, Mildred S. Dresselhaus, Riichiro Saito, Gene Dresselhaus

Raman spectroscopy is the inelastic scattering of light by matter. Being highly sensitive to the physical and chemical properties of materials, as well as to environmental effects that change these properties, Raman spectroscopy is now evolving into one of the most important tools for nanoscience and nanotechnology. In contrast to usual microscopyrelated techniques, the advantages of using light for nanoscience relate to both experimental and fundamental aspects.

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Computational Spectroscopy

Date: Oct 27, 2010

Author: Jorg Grunenberg

Unique in its comprehensive coverage of not only theoretical methods but also applications in computational spectroscopy, this ready reference and handbook compiles the developments made over the last few years, from single molecule studies to the simulation of clusters and the solid state, from organic molecules to complex inorganic systems and from basic research to commercial applications in the area of environment relevance. In so doing, it covers a multitude of apparatus-driven technologies, starting...

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Raman, Infrared, and Near-Infrared Chemical Imaging

Date: Oct 1, 2010

Author: Slobodan Sasic, Yukihiro Ozaki

An all-inclusive guide on the analytical methods of Raman, infrared, and near-infrared chemical imaging An underutilized technology, chemical imaging through Raman, infrared (IR), and near-infrared (NIR) is beginning to gain recognition for its non-destructive method of permitting visualization of spatially resolved chemical information. This type of analysis is triggering a groundswell of demand as manufactured materials become more complex and the need for greater scrutiny and less damaging research...

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Solid State NMR Studies of Biopolymers

Date: Aug 13, 2010

Author: Anne E. McDermott, Tatyana Polenova

The content of this volume has been added to the online reference work Encyclopedia of Magnetic Resonance. For further information see Encyclopedia of Magnetic Resonance. The field of solid state NMR of biological samples [ssNMR] has blossomed in the past 5-10 years, and a cohesive overview of the technology is needed for new practitioners in industry and academia. This title provides an overview of Solid State NMR methods for studying structure dynamics and ligand-binding in biopolymers, and offers an...

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Mass Spectrometry for Microbial Proteomics

Date: Jul 16, 2010

Author: Haroun N. Shah, Saheer E. Gharbia

New advances in proteomics, driven largely by developments in mass spectrometry, continue to reveal the complexity and diversity of pathogenic mechanisms among microbes that underpin infectious diseases. Therefore a new era in medical microbiology is demanding a rapid transition from current procedures to high throughput analytical systems for the diagnosis of microbial pathogens. This book covers the broad microbiological applications of proteomics and mass spectrometry. It is divided into six sections...

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