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Mass Spectrometry in Drug Metabolism and Pharmacokinetics
Date: Jan 16, 2009
Author: Ragu Ramanathan
This timely reference discusses mass spectrometry in drug metabolism and pharmacokinetic studies. With contributions by professionals from the pharmaceutical industry, this book begins with a review of current mass spectrometry techniques and applications, followed by discussions of various methods for using MS in drug metabolism studies and pharmacokinetics. Highlighting the critical importance of ADME studies for understanding how a drug is absorbed, distributed, metabolized, and excreted by the body,...
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Introduction to Proteomics
Date: Nov 7, 2008
Author: Agnieszka Kraj, Jerzy Silberring
Introduction to Proteomics is written by seasoned researchers with years of practical experience. In addition to comprehensive discussions of the basic concepts, techniques, and applications of the subject, the text also includes an extensive glossary and a chapter containing laboratory exercises and protocols. While mass spectrometry is central to proteomics, the book discusses all of the analytical techniques a student is likely to need when faced with real-world problems, such as sample preparation,...
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Fluorescence Methods and Applications: Spectroscopy, Imaging, and Probes
Date: Aug 8, 2008
Author: Otto S. Wolfbeis
This volume features papers on new spectroscopic methods and techniques, the development and application of fluorescent probes, and new techniques and applications of fluorescence imaging. Specific areas include the following: fluorescence lifetime, fluorescence (in vivo) imaging, time-resolved fluorescence, luminescence anisotropy, fluorescent (NMIR) labels, luminescent lanthanides, fluorescent sensors and probes, fluorescence microscopy, FRET, fluorescent nanoparticles and dots, high-throughput...
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Even Electron Mass Spectrometry with Biomolecule Applications
Date: May 20, 2008
Author: Bryan M. Ham
In addition to the essential theoretical background and fundamental principles, this unique reference presents a detailed, step-by-step methodology for interpreting even electron mass spectrometry results. Specific chapters are devoted to: proteomics; biomolecule spectral interpretation of small molecules; biomolecule spectral interpretation of biological macromolecules; and MALDI-TOF-Postsource Decay (PSD). Chapters feature detailed examples, questions, and problems to help readers solidify their...
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Preclinical Development Handbook: ADME and Biopharmaceutical Properties
Date: Apr 29, 2008
Author: Shayne Cox Gad
A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic, comprehensive reference to prioritizing and optimizing leads, dose formulation, ADME, pharmacokinetics, modeling, and regulations. This authoritative, easy-to-use resource covers all the issues that need to be considered and provides detailed instructions for...
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Preclinical Development Handbook: Toxicology
Date: Apr 29, 2008
Author: Shayne Cox Gad
A clear, straightforward resource to guide you through preclinical drug development Following this book's step-by-step guidance, you can successfully initiate and complete critical phases of preclinical drug development. The book serves as a basic,comprehensive reference to prioritizing and optimizing leads, toxicity, pharmacogenomics, modeling, and regulations. This single definitive, easy-to-use resource discusses all the issues that need consideration and provides detailed instructions for current...
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Trace Quantitative Analysis by Mass Spectrometry
Date: Apr 18, 2008
Author: Robert K. Boyd, Cecilia Basic, Robert A. Bethem
This book provides a serious introduction to the subject of mass spectrometry, providing the reader with the tools and information to be well prepared to perform such demanding work in a real-life laboratory. This essential tool bridges several subjects and many disciplines including pharmaceutical, environmental and biomedical analysis that are utilizing mass spectrometry: Covers all aspects of the use of mass spectrometry for quantitation purposes Written in textbook style to facilitate understanding...
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Practical Gamma-ray Spectroscopy, 2nd Edition
Date: Apr 18, 2008
Author: Gordon Gilmore
The Second Edition of Practical Gamma-Ray Spectrometry has been completely revised and updated, providing comprehensive coverage of the whole gamma-ray detection and spectrum analysis processes. Drawn on many years of teaching experience to produce this uniquely practical volume, issues discussed include the origin of gamma-rays and the issue of quality assurance in gamma-ray spectrometry. This new edition also covers the analysis of decommissioned nuclear plants, computer modelling systems for...
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Microsystem Engineering of Lab-on-a-Chip Devices
Date: Apr 16, 2008
Author: Oliver Geschke, Henning Klank, Pieter Telleman
Edited by an interdisciplinary team of scientists at one of the leading centers for microsystem research, this second edition retains the proven structure of its predecessor, enlarged by around 10%. Focusing on analytical applications mainly in life sciences, this is an invaluable companion for fast and automated analytical procedures, providing a concise practical approach to microtechnology.
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Vibrational Spectroscopy for Medical Diagnosis
Date: Mar 20, 2008
Author: Max Diem, Peter Griffiths, John M. Chalmers
Cancer is the second largest cause of death (after heart disease) in North America and Europe. Statistics from many countries serve constantly to inform us of how prevalent cancer is worldwide, even though one particular variation may be more predominant is one geographical region than another. The Traumatic cost in human lives, the dramatic cost of treatment and the need for rapidly advancing diagnoses and improving diagnostic methods for cancer, are clear for all to see. Current histopathological...
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