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Journal Highlight: Proteomic analysis of exosomes and Its application in HIV‐1 infection

Date: May 21, 2018

Author: spectroscopyNOW

This review focuses on exosome isolation and purification methods and their implications in HIV‐1 studies as well as the roles of proteomic techniques in defining exosomal contents and the research and clinical applications of proteomics and exosome in HIV‐1 biology.

Read More thumbnail image: Journal Highlight Proteomic analysis of exosomes and Its application in HIV1 infection

Sample preparation in proteomics: Method bias

Date: May 15, 2018

Author: Steve Down

A comparison of four commonly used proteomics sample preparation methods for head and neck tissues has revealed that there is no universal method, each having their own deficiencies and advantages.

Read More thumbnail image: Sample preparation in proteomics Method bias

Postmortem interval: Forensic proteomic pointers

Date: May 1, 2018

Author: Steve Down

A proteomics study of decaying bones has thrown up a number of proteins that might prove to be valuable markers of the skeletal postmortem interval as an aid to forensic scientists.

Read More thumbnail image: Postmortem interval Forensic proteomic pointers

Journal Highlight: Changes in the proteome of the problem weed blackgrass correlating with multiple herbicide resistance

Date: Apr 23, 2018

Author: spectroscopyNOW

The evolution of multiple herbicide resistance in populations of the weed blackgrass (Alopecurus myosuroides) has been investigated using a combination of transcriptomics and proteomics.

Read More thumbnail image: Journal Highlight Changes in the proteome of the problem weed blackgrass correlating with multiple herbicide resistance

Anton Checkov: Cause of death questioned

Date: Apr 15, 2018

Author: Steve Down

Proteome analysis of brown stains on archived personal items of Anton Checkov has yielded proteins related to Mycobacterium tuberculosis, confirming that he had tuberculosis at time of death, but another protein suggests that there may have been a different cause of death.

Read More thumbnail image: Anton Checkov Cause of death questioned

Asthma at work: Proteomics search for biomarkers

Date: Apr 1, 2018

Author: Steve Down

Nasal protein profiling has been used to measure the responses of people exposed to airborne allergens like isocyanates and welding fumes, leading to several candidate biomarkers for work-related asthma.

Read More thumbnail image: Asthma at work Proteomics search for biomarkers

Journal Highlight: Expression of CPPED1 in human trophoblasts is associated with timing of term birth

Date: Mar 26, 2018

Author: spectroscopyNOW

Proteomic analyses of full‐term placentas from uncomplicated pregnancies have been carried out to identify protein signatures associated with the onset of spontaneous delivery, implicating the involvement of CPPED1.

Read More thumbnail image: Journal Highlight Expression of CPPED1 in human trophoblasts is associated with timing of term birth

Mortality biomarkers: Peptides and proteins

Date: Mar 15, 2018

Author: Steve Down

A large-scale proteomics study on older men has identified a number of peptides and proteins that are associated with five-year mortality, most of them arising from non-cancer deaths and implicating a number of biological pathways, especially inflammation.

Read More thumbnail image: Mortality biomarkers Peptides and proteins

Breast cancer in young women: Biomarkers from breast milk

Date: Mar 1, 2018

Author: Steve Down

A preliminary proteomics study of breast milk in younger women collected within two years of them being diagnosed with breast cancer has revealed a number of dysregulated proteins as potential candidates for early detection of the disease.

Read More thumbnail image: Breast cancer in young women Biomarkers from breast milk

Journal Highlight: The human protein atlas: A spatial map of the human proteome

Date: Feb 19, 2018

Author: spectroscopyNOW

The Human Protein Atlas database functions and the ways that users can utilize them for their own research have been comprehensively described, along with the future path of spatial proteomics.

Read More thumbnail image: Journal Highlight The human protein atlas A spatial map of the human proteome
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