Proteomics & Genomics / Ezine
Journal Highlight: Transcriptomic and proteomic insights of the wine yeast biomass propagation process
Date: Dec 20, 2010
Author:
Transcriptome and proteome profiles have been established for the commercial wine yeast strain T73 during an important yeast biomass propagation, revealing that the metabolic transition from fermentation to respiration is the most critical step in biomass propagation.
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Population proteomics of hake: proteins can pinpoint the location of the fish
Date: Dec 15, 2010
Author: Steve Down
Three distinct populations of European hake have been distinguished by the levels of their liver and brain proteins, allowing fish classification according to origin. This should help in the monitoring and surveillance of fish stocks and prevent overfishing.
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Safety assessment of nanomaterials: proteomics predicts biomarkers of exposure to silica nanoparticles
Date: Dec 1, 2010
Author: Steve Down
Silica nanoparticles of different sizes induce increased levels of acute-phase proteins in the plasma of mice in a size-dependent manner following iv treatment. These proteins will be valuable indicators of exposure and could help to develop safer nanomaterials.
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Journal Highlight: Achievements and perspectives of top-down proteomics
Date: Nov 22, 2010
Author:
In this review article, the state-of-the-art of top-down approach is described along with its major advantages and drawbacks and the most recent trends are discussed, with references for all the covered topics reported in the text.
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Cockroach allergens identified: Personalised profiling of allergic people on the horizon
Date: Nov 15, 2010
Author: Steve Down
A comprehensive screening procedure has identified ten new allergenic proteins from the German cockroach and opens up the possibility of personalised profiling of individuals who suffer from cockroach allergies.
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The proteome of your pint: novel ligand capture technique uncovers more proteins
Date: Nov 1, 2010
Author: Steve Down
The proteome of beer has been examined using two peptide libraries to capture the proteins for subsequent identification, a technique which uncovered many trace proteins and could be used to help brewers alter the characteristics of the final product.
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Journal Highlight: Proteomic profiling reveals a catalogue of new candidate proteins for human skin aging
Date: Oct 25, 2010
Author:
A proteomic analysis of intrinsic human skin aging was carried out by quantifying proteins extracted and fluorescently labeled from sun-protected human foreskin samples pooled from 'young' and 'old' men.
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Counting calories: changes in the white adipose tissue proteome induced by caloric restriction
Date: Oct 15, 2010
Author: Steve Down
The proteome of rat white adipose tissue is affected by caloric restriction, say Spanish scientists, in different ways to the effects of aging. The positive changes include an improvement in oxidative stress and energy metabolism, which could lead to the identification of biomarkers of aging.
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Towards the male contraceptive
Date: Oct 1, 2010
Author: Steve Down
Proteins involved in regulating the heat-induced suppression of human spermatogenesis, which were identified in a proteomics study, can be considered potential targets for the development of male contraceptives.
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Using HPLC-mass spectrometry to teach proteomics concepts with problem-based techniques
Date: Sep 27, 2010
Author:
Practical instruction of proteomics concepts was provided using HPLC coupled with a mass selective detection system for the analysis of simulated protein digests, illustrating that complex concepts can be taught in the undergraduate biochemistry laboratory using a problem-based approach.
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