Proteomics & Genomics / Ezine
Chernobyl flax takes the flak
Date: Sep 15, 2010
Author: Steve Down
Flax plants grown in soil that is still contaminated following the Chernobyl incident displayed remarkably limited adaptive changes in the proteome in response to ionising radiation.
Read More
Not so cold storage
Date: Sep 1, 2010
Author: Steve Down
Storing human plasma at -30°C, rather than the -80°C recommended in current standard operating procedures, has no adverse effects on the abundances of high-molecular-weight proteins, say Spanish scientists. This will allow the analysis of far more samples by 2D-DIGE in the study of human disease.
Read More
Comparative physiological and proteomic responses to drought stress in two poplar species originating from different altitudes
Date: Aug 23, 2010
Author:
Cuttings of Populus kangdingensis C. Wang et Tung and Populus cathayana Rehder were examined during a single growing season in a greenhouse for comparative analysis of their physiological and proteomic responses to drought stress.
Read More
Modelling experience not required
Date: Aug 15, 2010
Author: Steve Down
A combined transcriptomic and proteomic approach has been used for the first time to construct a gene and protein data reference set for a marine fouling invertebrate, as a rapid alternative to whole genome sequencing.
Read More
Allergenic prawn proteins
Date: Aug 1, 2010
Author: Steve Down
The key major allergenic proteins in black tiger prawns were identified using immunoblotting and proteomics techniques, and a signature peptide for tropomyosin, the major allergen, was identified for future quantitative studies in the seafood industry.
Read More
Glioma pathophysiology: Insights emerging from proteomics
Date: Jul 26, 2010
Author:
A systematic review of multiple independent proteomic analyses of glioma combined with a network analysis of differentially expressed proteins has revealed a robust and cohesive network for glioblastoma.
Read More
Cue antigens for Q fever
Date: Jul 15, 2010
Author: Steve Down
A protein microarray containing almost 2000 open reading frames has been used to detect seroactive antigens for the bacterium Coxiella burnetti, the agent of Q fever. Some of the antigens were used in an immunostrip for disease diagnosis and are candidates for vaccines.
Read More
Better than snail's pace
Date: Jul 1, 2010
Author: Steve Down
The changes in protein expression in an embryonic snail as it develops from a shell-less to a shelled form have been tracked by Taiwanese scientists, using de novo peptide sequencing to counter the lack of gastropod genomic and proteomic data.
Read More
Investigation of the binding of Cr(III) complexes to bovine and human serum proteins: A proteomic approach
Date: Jun 28, 2010
Author:
The interactions of Cr(III) complexes with serum proteins and their internalization by U937 macrophage-like cells was studied by a proteomic approach, in the context of Co-Cr alloy-based implants.
Read More
A route to personalised therapy selection
Date: Jun 15, 2010
Author: Steve Down
The plasma proteomes of patients with glioblastoma multiforme brain tumours were used to classify the type of tumour and indicate which patients would respond best to immunotherapy, heralding a new approach to personal medicine.
Read More
