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Heart disease prediction: Urinary peptide signals

Date: Jun 1, 2015

Author: Steve Down

A panel of peptide biomarkers designed for differentiating between patients with or without coronary heart disease has now been used to predict coronary events in asymptomatic patients suffering from hypertension.

Read More thumbnail image: Heart disease prediction Urinary peptide signals

Journal Highlight: Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice: insights into mechanisms of familial Parkinson's disease

Date: May 25, 2015

Author: spectroscopyNOW

The differences in expressed brain proteome and phosphoproteome between PINK1-deficient mice and wild-type mice were identified, revealing several pathways involved in the pathogenesis of familial Parkinson's disease.

Read More thumbnail image: Journal Highlight Quantitative expression proteomics and phosphoproteomics profile of brain from PINK1 knockout mice insights into mechanisms of familial Parkinsons disease

Cereal allergens: Food processing effects revealed by proteomics

Date: May 15, 2015

Author: Steve Down

Processing wheat into couscous and barley into malt reduces the levels of many allergenic proteins, say Czech researchers, who showed that the iTRAQ mass spectrometric labelling system is a useful way to measure food allergens.

Read More thumbnail image: Cereal allergens Food processing effects revealed by proteomics

Genetically modified beans: Proteomics tells them apart

Date: May 1, 2015

Author: Steve Down

The proteomes of the leaves of genetically modified beans have been compared to their conventional counterparts, allowing a clear differentiation between the two forms of this important food crop.

Read More thumbnail image: Genetically modified beans Proteomics tells them apart

Journal Highlight: Nutriproteomics: Facts, concepts, and perspectives

Date: Apr 20, 2015

Author: spectroscopyNOW

This article presents basic approaches and concepts to address scientific questions in nutritional proteomics and discusses potential benefits of proteomics-based methodologies to help advance the field of molecular nutrition research.

Read More thumbnail image: Journal Highlight Nutriproteomics Facts concepts and perspectives

Thrombosis biomarkers: Proteins identify leukaemia patients at risk from asparaginase therapy

Date: Apr 15, 2015

Author: Steve Down

Proteomic analysis of the cerebrospinal fluid of children with acute lymphoblastic leukaemia under asparaginase therapy might be a way to identify those at risk from thrombosis, say US researchers.

Read More thumbnail image: Thrombosis biomarkers Proteins identify leukaemia patients at risk from asparaginase therapy

Salivary proteomics: Mammalian comparison

Date: Apr 4, 2015

Author: Steve Down

A comparison of the saliva proteomes of seven mammals from four evolutionary groups has revealed that most protein families are shared between species despite the high variability of individual proteins.

Read More thumbnail image: Salivary proteomics Mammalian comparison

Journal Highlight: Important options available — from start to finish — for translating proteomics results to clinical chemistry

Date: Mar 23, 2015

Author: spectroscopyNOW

Important options associated with the design, execution and interpretation of clinical proteomics studies for translation into clinical practice have been reviewed.

Read More thumbnail image: Journal Highlight Important options available  from start to finish  for translating proteomics results to clinical chemistry

Male infertility markers: Proteins influenced by reactive oxygen species

Date: Mar 15, 2015

Author: Steve Down

Proteins in infertile human sperm that are affected by low, medium and high excesses of reactive oxygen species have been identified, highlighting those that have reproductive functions.

Read More thumbnail image: Male infertility markers Proteins influenced by reactive oxygen species

Respiratory carbon nanotubes: Proteins secreted in lung fluid

Date: Mar 2, 2015

Author: Steve Down

Carbon nanotubes alter the proteome of the bronchoalveolar lavage fluid of mice, increasing the amounts of proteins associated with inflammation and immune response and pointing to the toxic response mechanism.

Read More thumbnail image: Respiratory carbon nanotubes Proteins secreted in lung fluid
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