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Journal Highlight: Recent advances in proteomics: towards the human proteome

Date: Jun 23, 2014

Author: spectroscopyNOW

This review summarizes the key discoveries that laid down the foundations for proteomics as we now know it, and describes key recent technological advances that will undoubtedly contribute to achieving the initial goal of the Human Proteome Organization.

Read More thumbnail image: Journal Highlight Recent advances in proteomics towards the human proteome

Colourful catfish: Protein clues to red tinge

Date: Jun 15, 2014

Author: Steve Down

Catfish fillets gain their reddish off-colour after being caught due to an excess of haemoglobin possibly brought on by stress, say researchers in the US.

Read More thumbnail image: Colourful catfish Protein clues to red tinge

Autistic proteins: Cholesterol metabolism and oxidative stress implicated

Date: Jun 2, 2014

Author: Steve Down

A transatlantic group of scientists has identified several proteins involved in cholesterol metabolism that have increased abundances in children with autism spectrum disorder, supporting speculation that oxidative stress might be a factor behind this condition.

Read More thumbnail image: Autistic proteins Cholesterol metabolism and oxidative stress implicated

Journal Highlight: Pathophysiology of tobacco smoke exposure: Recent insights from comparative and redox proteomics

Date: May 26, 2014

Author: spectroscopyNOW

Different quantitative and redox proteomic approaches that have been used to evaluate changes in protein expression and specific oxidative protein modifications induced by exposure to cigarette smoke are overviewed.

Read More thumbnail image: Journal Highlight Pathophysiology of tobacco smoke exposure Recent insights from comparative and redox proteomics

Blood sampling for proteomics: Anticoagulant comparison

Date: May 17, 2014

Author: Steve Down

The proteolytic profiles of human plasma treated with different anticoagulants and of untreated human serum have been compared in order to define the effects encountered during clinical proteomics and biomarker studies.

Read More thumbnail image: Blood sampling for proteomics Anticoagulant comparison

Alzheimer's prediction: Plasma metabolites are biomarkers

Date: May 2, 2014

Author: Steve Down

Two separate groups of metabolites found in human plasma can distinguish patients with Alzheimer’s disease or mild cognitive impairment from healthy people, providing a potential route to early diagnosis of both conditions.

Read More thumbnail image: Alzheimers prediction Plasma metabolites are biomarkers

Journal Highlight: Rice proteomics: A model system for crop improvement and food security

Date: Apr 21, 2014

Author: spectroscopyNOW

This review covers rice proteomics studies from August 2010 to July 2013, focusing on rice responses to diverse abiotic and biotic stresses, especially rice-pathogen interactions.

Read More thumbnail image: Journal Highlight Rice proteomics A model system for crop improvement and food security

Canine breast cancer: Model for human equivalent

Date: Apr 14, 2014

Author: Steve Down

Four proteins found in the serum of dogs with breast cancer have been reported to produce an autoantibody response on human breast cancer, strengthening the case for using the canine breast cancer as a model for the human form.

Read More thumbnail image: Canine breast cancer Model for human equivalent

Plant pathogens: How Salmonella changes when it attacks lettuce

Date: Apr 2, 2014

Author: Steve Down

A proteomics study has revealed the proteins that are affected in both species when salad bowl lettuce is infected with the Salmonella bacterium, those involved in ascorbate metabolism being especially important.

Read More thumbnail image: Plant pathogens How Salmonella changes when it attacks lettuce

Journal Highlight: Understanding the pathogenesis of endometriosis through proteomics: Recent advances and future prospects

Date: Mar 24, 2014

Author: spectroscopyNOW

The future of human endometriosis proteomics is discussed and the proteomic advances made so far in understanding the molecular basis of endometriosis are presented.

Read More thumbnail image: Journal Highlight Understanding the pathogenesis of endometriosis through proteomics Recent advances and future prospects
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