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Blood sampling for proteomics: Anticoagulant comparison

Date: May 17, 2014

Author: Steve Down

The proteolytic profiles of human plasma treated with different anticoagulants and of untreated human serum have been compared in order to define the effects encountered during clinical proteomics and biomarker studies.

Read More thumbnail image: Blood sampling for proteomics Anticoagulant comparison

Alzheimer's prediction: Plasma metabolites are biomarkers

Date: May 2, 2014

Author: Steve Down

Two separate groups of metabolites found in human plasma can distinguish patients with Alzheimer’s disease or mild cognitive impairment from healthy people, providing a potential route to early diagnosis of both conditions.

Read More thumbnail image: Alzheimers prediction Plasma metabolites are biomarkers

Journal Highlight: Rice proteomics: A model system for crop improvement and food security

Date: Apr 21, 2014

Author: spectroscopyNOW

This review covers rice proteomics studies from August 2010 to July 2013, focusing on rice responses to diverse abiotic and biotic stresses, especially rice-pathogen interactions.

Read More thumbnail image: Journal Highlight Rice proteomics A model system for crop improvement and food security

Canine breast cancer: Model for human equivalent

Date: Apr 14, 2014

Author: Steve Down

Four proteins found in the serum of dogs with breast cancer have been reported to produce an autoantibody response on human breast cancer, strengthening the case for using the canine breast cancer as a model for the human form.

Read More thumbnail image: Canine breast cancer Model for human equivalent

Plant pathogens: How Salmonella changes when it attacks lettuce

Date: Apr 2, 2014

Author: Steve Down

A proteomics study has revealed the proteins that are affected in both species when salad bowl lettuce is infected with the Salmonella bacterium, those involved in ascorbate metabolism being especially important.

Read More thumbnail image: Plant pathogens How Salmonella changes when it attacks lettuce

Journal Highlight: Understanding the pathogenesis of endometriosis through proteomics: Recent advances and future prospects

Date: Mar 24, 2014

Author: spectroscopyNOW

The future of human endometriosis proteomics is discussed and the proteomic advances made so far in understanding the molecular basis of endometriosis are presented.

Read More thumbnail image: Journal Highlight Understanding the pathogenesis of endometriosis through proteomics Recent advances and future prospects

Frozen out: Sperm proteins affected by cryopreservation

Date: Mar 15, 2014

Author: Steve Down

The first proteomics study of cryopreserved human sperm has revealed that the process changes the protein content, largely due to degradation and phosphorylation.

Read More thumbnail image: Frozen out Sperm proteins affected by cryopreservation

Ancient bone proteome: Long-lived proteins

Date: Mar 1, 2014

Author: Steve Down

Proteome analysis of a number of fossil bones has been used to show how the protein content evolves over one million years, several non-collagenous proteins surviving for very long periods.

Read More thumbnail image: Ancient bone proteome Long-lived proteins

Journal Highlight: Proteomics in environmental and technical microbiology

Date: Feb 24, 2014

Author: spectroscopyNOW

This review presents results of proteomic studies carried out in areas such as fundamental microbiological research and biotechnology and addresses the emerging field of metaproteomics.

Read More thumbnail image: Journal Highlight Proteomics in environmental and technical microbiology

Tracking tuberculosis: Panel of protein biomarkers in serum

Date: Feb 15, 2014

Author: Steve Down

A set of four biomarkers for pulmonary tuberculosis has been identified by Chinese scientists using proteome investigations on serum, giving a far higher predictability than any of the biomarkers alone.

Read More thumbnail image: Tracking tuberculosis Panel of protein biomarkers in serum
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