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Canine breast cancer: Model for human equivalent

Date: Apr 14, 2014

Author: Steve Down

Four proteins found in the serum of dogs with breast cancer have been reported to produce an autoantibody response on human breast cancer, strengthening the case for using the canine breast cancer as a model for the human form.

Read More thumbnail image: Canine breast cancer Model for human equivalent

Plant pathogens: How Salmonella changes when it attacks lettuce

Date: Apr 2, 2014

Author: Steve Down

A proteomics study has revealed the proteins that are affected in both species when salad bowl lettuce is infected with the Salmonella bacterium, those involved in ascorbate metabolism being especially important.

Read More thumbnail image: Plant pathogens How Salmonella changes when it attacks lettuce

Journal Highlight: Understanding the pathogenesis of endometriosis through proteomics: Recent advances and future prospects

Date: Mar 24, 2014

Author: spectroscopyNOW

The future of human endometriosis proteomics is discussed and the proteomic advances made so far in understanding the molecular basis of endometriosis are presented.

Read More thumbnail image: Journal Highlight Understanding the pathogenesis of endometriosis through proteomics Recent advances and future prospects

Frozen out: Sperm proteins affected by cryopreservation

Date: Mar 15, 2014

Author: Steve Down

The first proteomics study of cryopreserved human sperm has revealed that the process changes the protein content, largely due to degradation and phosphorylation.

Read More thumbnail image: Frozen out Sperm proteins affected by cryopreservation

Ancient bone proteome: Long-lived proteins

Date: Mar 1, 2014

Author: Steve Down

Proteome analysis of a number of fossil bones has been used to show how the protein content evolves over one million years, several non-collagenous proteins surviving for very long periods.

Read More thumbnail image: Ancient bone proteome Long-lived proteins

Journal Highlight: Proteomics in environmental and technical microbiology

Date: Feb 24, 2014

Author: spectroscopyNOW

This review presents results of proteomic studies carried out in areas such as fundamental microbiological research and biotechnology and addresses the emerging field of metaproteomics.

Read More thumbnail image: Journal Highlight Proteomics in environmental and technical microbiology

Tracking tuberculosis: Panel of protein biomarkers in serum

Date: Feb 15, 2014

Author: Steve Down

A set of four biomarkers for pulmonary tuberculosis has been identified by Chinese scientists using proteome investigations on serum, giving a far higher predictability than any of the biomarkers alone.

Read More thumbnail image: Tracking tuberculosis Panel of protein biomarkers in serum

Brain dead: Polybrominated diphenyl ethers alter proteins in neural stem cells

Date: Feb 1, 2014

Author: Steve Down

The polybrominated fire retardants that are widely used in consumer products could be acting as neurotoxins in the brain because they affect the abundance of some key proteins in neural stem/progenitor cells.

Read More thumbnail image: Brain dead Polybrominated diphenyl ethers alter proteins in neural stem cells

Journal Highlight: Non-enzymatic glycation and glycoxidation protein products in foods and diseases: An interconnected, complex scenario fully open to innovative proteomic studies

Date: Jan 27, 2014

Author: spectroscopyNOW

The different aspects and methodologies related to microwave-assisted extraction of botanical materials that were subjected to experimental design have been reviewed, along with some general chemometric tools and the steps involved in its practice.

Read More thumbnail image: Journal Highlight Non-enzymatic glycation and glycoxidation protein products in foods and diseases An interconnected complex scenario fully open to innovative proteomic studies

Not carrying much weight: Microgravity affects brain proteins via oxidative stress

Date: Jan 16, 2014

Author: Steve Down

Simulated microgravity in rats causes oxidative stress, affecting many signalling pathways in the hypothalamus that are involved in basic processes like the sleeping/waking cycle and drinking behaviour, say Chinese researchers.

Read More thumbnail image: Not carrying much weight Microgravity affects brain proteins via oxidative stress
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