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Journal Highlight: Proteomics analysis of tumor microenvironment: Implications of metabolic and oxidative stresses in tumorigenesis

Date: Aug 26, 2013

Author: spectroscopyNOW

Recent advances in the understanding of the metabolic and oxidative stresses associated with tumor progression with proteomics-based systems biology approaches are highlighted.

Read More thumbnail image: Journal Highlight Proteomics analysis of tumor microenvironment Implications of metabolic and oxidative stresses in tumorigenesis

A joint effort: Differentiating types of arthritis

Date: Aug 15, 2013

Author: Steve Down

Four common types of arthritis share a common metabolic profile but there are sufficient variations to provide individual signatures for each disease, according to an international study.

Read More thumbnail image: A joint effort Differentiating types of arthritis

Vampire diaries: Protein evolution in bat venom

Date: Aug 1, 2013

Author: Steve Down

The venom of the common vampire bat contains a far more complex set of proteins than previously thought, thanks to an international study which identified new isoforms of other mammalian proteins and considered their molecular evolution.

Read More thumbnail image: Vampire diaries Protein evolution in bat venom

Journal Highlight: The proteomes of feedstocks used for the production of second-generation ethanol: a lacuna in the biofuel era

Date: Jul 22, 2013

Author: spectroscopyNOW

Proteomics research is reviewed for maize, sorghum, sugarcane, switchgrass and miscanthus, which are the main crops suggested as potential sources of lignocellulosic biomass for the production of second-generation ethanol.

Read More thumbnail image: Journal Highlight The proteomes of feedstocks used for the production of second-generation ethanol a lacuna in the biofuel era

Eye contact: Proteins implicated in wet age-related macular degeneration

Date: Jul 15, 2013

Author: Steve Down

A number of potential biomarkers for wet age-related macular degeneration have been identified in a proteomics study on the aqueous humour of Chinese patients, which might lead to new treatments for the disease.

Read More thumbnail image: Eye contact Proteins implicated in wet age-related macular degeneration

Tissue repair: Antioxidant influences processes in rainbow trout

Date: Jul 3, 2013

Author: Steve Down

The proteins involved in tissue damage and repair in the rainbow trout have been identified as an example of a lower vertebrate used in food production, those fish fed on the antioxidant astaxanthin having a different cellular response.

Read More thumbnail image: Tissue repair Antioxidant influences processes in rainbow trout

Journal Highlight: Tissue proteomics of the low-molecular weight proteome using an integrated cLC-ESI-QTOFMS approach

Date: Jun 24, 2013

Author: spectroscopyNOW

A tissue proteomics approach involving tissue homogenization followed by depletion of large proteins and then capillary LC-MS analysis has been evaluated for examining the low molecular weight/low abundance tissue proteome.

Read More thumbnail image: Journal Highlight Tissue proteomics of the low-molecular weight proteome using an integrated cLC-ESI-QTOFMS approach

Microbore protein digestor: Hollow fibre reactor for online proteolysis

Date: Jun 15, 2013

Author: Steve Down

A microbore enzyme reactor constructed from a hollow fibre that is linked directly to an LC/MS system has been designed for the online digestion, purification and analysis of low amounts of proteins.

Read More thumbnail image: Microbore protein digestor Hollow fibre reactor for online proteolysis

Pancreatic poser: Interspecies effects of nicotine on proteome

Date: Jun 1, 2013

Author: Steve Down

Nicotine affects pancreatic stellate cells from different species in similar ways, suggesting common interaction pathways that will help to understand the link between smoking and pancreatic disease, say researchers in the US.

Read More thumbnail image: Pancreatic poser Interspecies effects of nicotine on proteome

Journal Highlight: Proteomics applied to transfusion plasma: the beginning of the story

Date: May 20, 2013

Author: spectroscopyNOW

The principles of proteomics analysis and the state of the art applied to plasma analysis are presented, along with the use of proteomics for assessing the impact of storage conditions and pathogen inactivation treatments on transfusion plasma.

Read More thumbnail image: Journal Highlight Proteomics applied to transfusion plasma the beginning of the story
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